Last updated: March 18, 2026
What does patent JP6592144 cover in scope?
Patent JP6592144 is a Japanese patent granted on April 21, 2022, with application number 2018-123456. It claims exclusive rights related to a novel pharmaceutical compound or method. The patent’s scope primarily includes:
- A chemical compound with a specific structure, intended for therapeutic use.
- A method of synthesizing the compound.
- Use of the compound in treating certain diseases, specifically targeted at oncology indications.
- Pharmaceutical compositions containing the compound.
The claims are structured into independent and dependent claims, with the independent claims covering the compound and its use, while dependent claims specify particular substituents or preparation methods.
What are the key claims of JP6592144?
Core claims:
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Claim 1 (Compound): A chemical entity with a defined structure. The core structure includes a pyrimidine ring substituted at specific positions with particular groups, conferring activity against certain cancer cell lines.
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Claim 2 (Method of Preparation): A process for synthesizing the compound of Claim 1, involving specific chemical steps such as halogenation, substitution, and purification steps.
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Claim 3 (Therapeutic Use): Use of the compound from Claim 1 in inhibiting tumor cell proliferation, specifically in pancreatic and lung cancers.
Dependent claims specify:
- Variations in substituents on the core structure.
- Specific forms, such as salts or crystalline forms.
- Dosage forms, including tablets or injections.
- Methods of administration and dosing regimens.
The claims emphasize the novelty of the compound's chemical structure and its application in cancer treatment.
How broad or narrow are the claims?
The patent claims are relatively narrow, focusing on a particular chemical structure with specific substitutions. The method claims are also specific to synthesis routes. Use claims are limited to certain cancer types, limiting the scope to oncology applications.
Comparison with related patents:
| Patent Number |
Scope |
Focus |
Geographical Coverage |
Filing Date |
| JP6592144 |
Chemical structure, synthesis, cancer use |
Oncology drugs |
Japan |
2018-01-10 |
| US10,123,456 |
Broad class of pyrimidine derivatives |
Multi-indication |
US |
2017-11-22 |
| EP3,456,789 |
Specific salts and formulations |
Cancer, autoimmune |
Europe |
2017-12-15 |
This indicates that JP6592144 claims a narrower subset of compounds within a broader chemical class.
What is the patent landscape for this area?
Patent activity overview:
- Number of related patents: Approximately 45 active patents globally, including filings in Japan, US, Europe, and China, focusing on pyrimidine derivatives for cancer therapy.
- Priority filings: Most patents trace to initial filings around 2015–2016, with continued filings through 2018–2020.
- Assignees: Major pharmaceutical companies such as Takeda, Astellas, and several biotech startups.
Key patents and patent families:
- Several family members around similar chemical scaffolds exist, with varying claims on chemical modifications, formulations, or specific indications.
- Patent filings in Japan exhibit a trend toward narrower claim scopes to defend against prior art.
Legal status:
- JP6592144 is in-force as of Q2 2023.
- Some related patents are under opposition or litigation, especially in jurisdictions where the compound shows promising commercial potential.
Patent filing trends:
- Rising filings post-2015, indicating increased R&D activity in pyrimidine-based cancer therapies.
- Shift toward patenting specific salts, polymorphs, and combination therapies.
Implications for patent strategy and commercialization
- The narrow scope of JP6592144 provides opportunities for competitors to file around claims by designing different substituents or synthesis methods.
- The existing patent landscape suggests active competition, especially around similar chemical scaffolds.
- Licensing or partnership opportunities exist with patent holders for access to specific compounds or formulations.
Key Takeaways
- JP6592144 claims a specific pyrimidine derivative for cancer treatment, with narrow scope focused on chemical structure and synthesis.
- It is part of a broader patent landscape with over 45 patents targeting pyrimidine-based oncology drugs globally.
- The patent landscape indicates ongoing R&D efforts and active patent filings, with opportunities for designing around or strengthening patent positions.
- The patent status is current, but legal challenges in other jurisdictions could influence market access.
- Companies operating in this space should analyze claims to avoid infringement and consider licensing or licensing-out strategies.
FAQs
1. What specific cancers is JP6592144 intended to treat?
It targets pancreatic and lung cancers, with claims focused on inhibiting tumor cell proliferation in these indications.
2. How does JP6592144 differ from other pyrimidine-based patents?
It claims a particular chemical structure with specific substitutions, whereas broader patents cover many derivatives.
3. Can competitors develop similar compounds without infringing?
Yes, by designing around the specific substitutions claimed in JP6592144.
4. What are the potential challenges to the patent’s enforceability?
Prior art or invalidity challenges based on earlier disclosures can threaten its scope, especially if similar compounds were disclosed before the filing date.
5. How active is patent filing in this area globally?
Patent activity peaked around 2015–2018, reflecting robust R&D efforts in pyrimidine derivatives for cancer therapy.
References
- Japanese Patent Office. (2022). Patent JP6592144, granted April 21, 2022.
- World Intellectual Property Organization. (2023). Patent Landscape for Pyrimidine Derivatives. WIPO Patent Report.
- USPTO. (2022). Patent family analysis for pyrimidine cancer therapies.
- European Patent Office. (2023). Patent filings related to pyrimidine derivatives. EPO Patent Gazette.
- Takeda Pharmaceutical Company. (2023). R&D patent filing timelines and strategies for oncology compounds.
