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Deferiprone - Generic Drug Details

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What are the generic drug sources for deferiprone and what is the scope of deferiprone patent protection?

Deferiprone is the generic ingredient in two branded drugs marketed by Apopharma Inc and Taro Pharm Inds Ltd, and is included in three NDAs. There are two patents protecting this compound and one Paragraph IV challenge. Additional information is available in the individual branded drug profile pages.

Deferiprone has forty-two patent family members in twenty-four countries.

There are four drug master file entries for deferiprone. Two suppliers are listed for this compound.

Summary for deferiprone

International Patents:	42
US Patents:	2
Tradenames:	2
Applicants:	2
NDAs:	3
Drug Master File Entries:	4
Suppliers / Packagers:	2
Bulk Api Vendors:	92
Clinical Trials:	57
Patent Applications:	1,175
Formulation / Manufacturing:	see details
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for deferiprone
DailyMed Link:	deferiprone at DailyMed

Pharmacology for deferiprone

Drug Class	Iron Chelator
Mechanism of Action	Iron Chelating Activity

Synonyms for deferiprone

1,2-dimethyl-3-hydroxy-4-pyridinone

1,2-dimethyl-3-hydroxy-4-pyridone

1,2-Dimethyl-3-hydroxy-4-pyridone, 99+%

1,2-Dimethyl-3-hydroxy-4(1H)-pyridinone

1,2-Dimethyl-3-hydroxypyrid-4-one

1,2-Dimethyl-3-hydroxypyridine-4-one

1,2-dimetyl-3-hydroxy-4-pyridinone

2BTY8KH53L

3-hydroxy-1,2-dimethyl-4- pyridinone

3-Hydroxy-1,2-dimethyl-4-pyridinone

3-hydroxy-1,2-dimethyl-4(1H)-pyridinone

3-Hydroxy-1,2-dimethyl-4(1H)-pyridone

3-Hydroxy-1,2-dimethyl-4(1H)-pyridone, 98%

3-Hydroxy-1,2-dimethyl-4(1H)pyridinone

3-hydroxy-1,2-dimethyl-pyridin-4-one

3-hydroxy-1,2-dimethylhydropyridin-4-one

3-hydroxy-1,2-dimethylpyrid-4-one

3-hydroxy-1,2-dimethylpyridin-4-one

3-hydroxy-1,2-dimethylpyridin-4(1H)-one

30652-11-0

3231AB

4(1H)-Pyridinone, 1,2-dimethyl-3-hydroxy-

4(1H)-Pyridinone, 3-hydroxy-1,2-dimethyl-

4(1H)-Pyridone, 3-hydroxy-1,2-dimethyl-

4(1H)-Pyridone, 3-hydroxy-1,2-dimethyl- (8CI)

AB00572605_11

AB00572605_12

AC1L1EVW

AC1Q3YW0

ACMC-209hhl

AJ-08273

AK112338

AKOS015902286

ANW-26935

API0002235

APO-066

APO-66

AX8010603

BB_SC-12066

BCP09606

BP-12415

BRN 1447108

C-01884

CAS-30652-11-0

CC-02933

CCG-100760

CCRIS 8318

CGP-37391

CHEBI:68554

CHEMBL70927

CP020

CP20

CP20 (Chelating agent)

CPD000059136

CRMD-001

CS-5240

D07416

DB-047826

DB08826

Deferidone

deferiprone (dfp)

Deferiprone (INN)

Deferiprone (USAN/INN)

Deferiprone [BAN:INN]

Deferiprone [USAN:INN:BAN]

Deferum

DN-180-01-AF

DS-5493

DSSTox_CID_20666

DSSTox_GSID_40666

DSSTox_RID_79529

DTXSID6040666

EX-A972

FCH1115379

Ferriprox

Ferriprox (TN)

FT-0606424

GTPL7456

HK-1

HMS2051C05

HMS2232E24

HMS3264P17

HMS3393C05

HSDB 8335

HY-B0568

I14-13353

InChI=1/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3

KB-32094

KS-00000FAB

L-1[chelating agent]

L1

LS-133035

MCULE-6406005067

MFCD00134497

MFCD00134497 (98%)

MLS000069481

MLS000758227

MLS001424029

MLS006011689

MolPort-001-792-505

NC00010

NCGC00090548-01

NCGC00090548-02

NSC-758880

NSC758880

Opera_ID_366

OR322144

Pharmakon1600-01504512

PL1

s4067

SAM001247015

SBB006753

SBI-0207041.P001

SC-16614

SCHEMBL94474

SMR000059136

SR-01000721891

SR-01000721891-4

ST093416

ST24028539

SY052576

TC-115680

Tox21_112429

TRA0004923

TZXKOCQBRNJULO-UHFFFAOYSA-

TZXKOCQBRNJULO-UHFFFAOYSA-N

UNII-2BTY8KH53L

VP13942

ZB000634

ZINC6226

US Patents and Regulatory Information for deferiprone

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Apopharma Inc	FERRIPROX	deferiprone	TABLET;ORAL	021825-001	Oct 14, 2011		RX	Yes	Yes
Apopharma Inc	FERRIPROX	deferiprone	SOLUTION;ORAL	208030-002	Apr 20, 2018		RX	Yes	No			Y
Apopharma Inc	FERRIPROX	deferiprone	SOLUTION;ORAL	208030-001	Sep 9, 2015		RX	Yes	Yes			Y

International Patents for deferiprone

Country	Patent Number	Estimated Expiration
Canada	2722393
Canada	2313270
Spain	2324978