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Generated: July 17, 2018

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Bexarotene - Generic Drug Details

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What are the generic sources for bexarotene and what is the scope of bexarotene patent protection?

Bexarotene
is the generic ingredient in two branded drugs marketed by Amerigen Pharms Ltd, Bionpharma Inc, and Valeant Luxembourg, and is included in four NDAs. Additional information is available in the individual branded drug profile pages.

There are seven drug master file entries for bexarotene. Five suppliers are listed for this compound.
Pharmacology for bexarotene
Ingredient-typeRetinoids
Drug ClassRetinoid
Synonyms for bexarotene
153559-49-0
166175-31-1
3-methyl-TTNEB
4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl)benzoic acid
4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid
4-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)benzoic acid
4-[1-(1,1,4,4,7-pentamethyltetralin-6-yl)vinyl]benzoic acid
4-[1-(3,5,5,8,8-Pentamethyl-2-5,8-dihydronaphthyl)vinyl]benzoic acid
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl]benzoic acid
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]benzoic acid
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-vinyl]benzoic acid
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid
4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid
4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid
4-[1-(5,6,7,8-TETRAHYDRO-3,5,5,8,8-PENTAMETHYL-2-N
4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-ethenyl]benzoic acid
4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid
4-[1-3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthaleneyl)vinyl]benzene carboxylic acid
42161-EP2295426A1
42161-EP2295427A1
42161-EP2298768A1
42161-EP2308861A1
42161-EP2311808A1
42161-EP2311829A1
42161-EP2311840A1
4k6i
559B490
9RA
A61RXM4375
A809441
AB0009892
AB01275475_02
AB01275475-01
AB2000502
AC-24569
AC1L32UG
ACT03911
AJ-26838
AK-64115
AKOS015902814
AN-616
AOB1247
AT-22934
BCP0726000106
BCP9000396
BDBM50032675
Benzoic acid, 4-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)-
Benzoic acid,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-
Bexaroten
Bexarotene (JAN/USAN/INN)
Bexarotene (USAN/INN)
Bexarotene [USAN:INN:BAN]
Bexarotene [USAN]
Bexarotene oral(targretin)
Bexarotene, >=98% (HPLC)
bexaroteno
bexarotenum
BG0619
BIDD:PXR0021
CAS-153559-49-0
CCG-221823
CHEBI:50859
CHEMBL1023
CS-0626
CTK8E7385
D03106
D0N0RU
DB00307
DL-298
DSSTox_CID_20619
DSSTox_GSID_40619
DSSTox_RID_79514
DTXSID1040619
Elan brand of bexarotene
FT-0657110
FT-0702645
GTPL2807
HMS2089L14
HMS3655D19
HSDB 7453
HY-14171
I14-1941
J-009026
J-519847
KB-188553
KS-00000NW6
LG 100069
LG 1069
LG 69
LG-100069
LG100069
LG1069
LG69 compound
LGD 1069
LGD-1069
LGD1069
Ligand brand of bexarotene
LS-38306
MCULE-3783114634
MFCD00932428
MLS006010146
MolPort-003-845-030
NAVMQTYZDKMPEU-UHFFFAOYSA-N
NCGC00181016-01
NCGC00181016-02
NCGC00181016-03
NCGC00181016-04
NCGC00255426-01
NSC-747528
NSC747528
OR069389
OR126219
OR126220
OR224989
p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid
p-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl]benzoic acid
QCR-117
RL01964
Ro 26-4455
RTX-011348
s2098
SBB067189
SC-19638
SC-50515
SCHEMBL9025
SMR001614557
SR 11247
SR-05000001480
SR-05000001480-2
SS-4628
ST24046138
Targret
Targretin
Targretin (TN)
Targretin-gel
Targretyn
Targrexin
Tox21_112666
Tox21_112666_1
Tox21_302407
UNII-A61RXM4375
W-5228
ZINC1539579

US Patents and Regulatory Information for bexarotene

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Bionpharma Inc BEXAROTENE bexarotene CAPSULE;ORAL 203174-001 Aug 12, 2014 AB RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Amerigen Pharms Ltd BEXAROTENE bexarotene CAPSULE;ORAL 209861-001 May 8, 2018 AB RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Valeant Luxembourg TARGRETIN bexarotene GEL;TOPICAL 021056-001 Jun 28, 2000 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Valeant Luxembourg TARGRETIN bexarotene CAPSULE;ORAL 021055-001 Dec 29, 1999 AB RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for bexarotene

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Valeant Luxembourg TARGRETIN bexarotene GEL;TOPICAL 021056-001 Jun 28, 2000 ➤ Sign Up ➤ Sign Up
Valeant Luxembourg TARGRETIN bexarotene CAPSULE;ORAL 021055-001 Dec 29, 1999 ➤ Sign Up ➤ Sign Up
Valeant Luxembourg TARGRETIN bexarotene CAPSULE;ORAL 021055-001 Dec 29, 1999 ➤ Sign Up ➤ Sign Up
Valeant Luxembourg TARGRETIN bexarotene CAPSULE;ORAL 021055-001 Dec 29, 1999 ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Federal Trade Commission
Cantor Fitzgerald
Mallinckrodt
US Army
Chubb
Fish and Richardson
Merck
Dow
McKinsey

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