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Last Updated: December 28, 2025

AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE - Generic Drug Details


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What are the generic drug sources for amino acids; magnesium chloride; potassium phosphate, dibasic; sodium acetate; sodium chloride and what is the scope of freedom to operate?

Amino acids; magnesium chloride; potassium phosphate, dibasic; sodium acetate; sodium chloride is the generic ingredient in six branded drugs marketed by Baxter Hlthcare and is included in three NDAs. Additional information is available in the individual branded drug profile pages.

Summary for AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE
Recent Clinical Trials for AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Nextrast, Inc.PHASE1
Mario Negri Institute for Pharmacological ResearchPHASE3
BeiGenePHASE2

See all AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE clinical trials

US Patents and Regulatory Information for AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Baxter Hlthcare TRAVASOL 8.5% W/ ELECTROLYTES amino acids; magnesium chloride; potassium phosphate, dibasic; sodium acetate; sodium chloride INJECTABLE;INJECTION 017493-002 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
Baxter Hlthcare TRAVASOL 3.5% W/ ELECTROLYTES amino acids; magnesium chloride; potassium phosphate, dibasic; sodium acetate; sodium chloride INJECTABLE;INJECTION 017493-003 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
Baxter Hlthcare TRAVASOL 5.5% SULFITE FREE W/ ELECTROLYTES IN PLASTIC CONTAINER amino acids; magnesium chloride; potassium phosphate, dibasic; sodium acetate; sodium chloride INJECTABLE;INJECTION 020173-001 Oct 27, 1995 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
Baxter Hlthcare TRAVASOL 3.5% SULFITE FREE W/ ELECTROLYTES IN PLASTIC CONTAINER amino acids; magnesium chloride; potassium phosphate, dibasic; sodium acetate; sodium chloride INJECTABLE;INJECTION 020177-001 Oct 23, 1995 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
Baxter Hlthcare TRAVASOL 8.5% SULFITE FREE W/ ELECTROLYTES IN PLASTIC CONTAINER amino acids; magnesium chloride; potassium phosphate, dibasic; sodium acetate; sodium chloride INJECTABLE;INJECTION 020173-002 Oct 27, 1995 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
Baxter Hlthcare TRAVASOL 5.5% W/ ELECTROLYTES amino acids; magnesium chloride; potassium phosphate, dibasic; sodium acetate; sodium chloride INJECTABLE;INJECTION 017493-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Market Dynamics and Financial Trajectory for Selected Pharmaceutical Chemicals: Amino Acids, Magnesium Chloride, Potassium Phosphate Dibasic, Sodium Acetate, and Sodium Chloride

Last updated: July 30, 2025

Introduction

The pharmaceutical landscape relies heavily on fundamental chemical ingredients, including amino acids and mineral salts. These compounds serve essential functions across therapeutic, nutritional, and manufacturing domains, driving substantial market demand. Their market dynamics and financial trajectories are shaped by evolving healthcare needs, manufacturing innovations, regulatory landscapes, and macroeconomic forces. This report dissects the current market status, future outlook, and key factors influencing the financial performance of amino acids, magnesium chloride, potassium phosphate dibasic, sodium acetate, and sodium chloride.

Market Overview

Amino Acids

Amino acids are organic compounds pivotal for protein synthesis and metabolic processes. They are instrumental in pharmaceutical formulations, nutritional supplements, and as raw materials in biotech manufacturing [1].

  • Market Size & Growth: Global amino acids market was valued at approximately USD 4.1 billion in 2022, with a compound annual growth rate (CAGR) projecting around 7.2% through 2028 [1].
  • Drivers: Rising demand for dietary supplements, innovative drug development, and growth in pet care and aquaculture sectors.
  • Challenges: Pricing pressures, strict regulatory standards, and volatility in raw material supply.

Magnesium Chloride

Magnesium chloride finds extensive applications in health supplements, bath salts, and pharmaceutical excipients given its bioavailability and mineral benefits [2].

  • Market Size & Growth: Estimated to expand at a CAGR of 5-6%, reaching USD 1.9 billion by 2027.
  • Drivers: Growing awareness of magnesium deficiency, increasing use in intravenous therapies, and sports nutrition.
  • Challenges: Quality control and sourcing consistency from natural deposits.

Potassium Phosphate Dibasic

This inorganic salt serves as a supplement, buffering agent, and in electrolyte replacement therapies [3].

  • Market Size & Growth: Market anticipated to grow steadily at 4-5% CAGR, driven by increasing demand for parenteral nutrition products.
  • Drivers: Aging populations, rising prevalence of electrolyte imbalance, and corporate R&D efforts.
  • Challenges: Supply chain complexities and regulatory hurdles surrounding injectable forms.

Sodium Acetate

Sodium acetate is predominantly employed in pharmaceutical manufacturing, buffer solutions, and dialysis applications [4].

  • Market Size & Growth: Projected CAGR of around 4%, with increasing growth in biopharmaceutical manufacturing.
  • Drivers: Climb in bio-manufacturing scale, expanding dialysis market, and need for stable buffering agents.
  • Challenges: Competition from alternative buffering agents.

Sodium Chloride

As a fundamental saline solution, sodium chloride is widely used in infusion therapy, drug diluents, and laboratory procedures [5].

  • Market Size & Growth: The largest among listed compounds, with a market size exceeding USD 5 billion, growing steadily at approximately 3-4% CAGR.
  • Drivers: Constant demand in hospitals, research, and manufacturing.
  • Challenges: Fluctuations in raw material pricing and sustainability concerns.

Market Dynamics

Driving Factors

  1. Healthcare Expansion: Aging populations and increased chronic disease prevalence bolster demand across therapeutic and nutritional sectors.
  2. Manufacturing Advancements: Technological improvements in extraction, synthesis, and purity standards accelerate supply chain efficiency.
  3. Regulatory Support: Stringent standards promote high-quality, GMP-compliant production, bolstering market credibility.
  4. R&D Investment: Increased pharmaceutical R&D activity leads to innovative formulations incorporating these chemicals.

Restraints and Challenges

  1. Raw Material Volatility: Natural deposits (e.g., mineral sources for magnesium chloride) face environmental restrictions affecting supply and pricing.
  2. Regulatory Barriers: Evolving safety and quality standards impose additional costs and delays.
  3. Environmental Concerns: Sustainable sourcing and waste management pose operational challenges.
  4. Price Competition: Market entrants and generic formulations exert downward pressure on pricing.

Emerging Trends

  • Bio-based Production: Growing focus on sustainable, plant-based extraction methods for amino acids.
  • Customization & Formulation Innovation: Tailoring compounds for targeted therapies and personalized medicine.
  • Digitalization & Supply Chain Optimization: Use of AI-driven analytics enhances forecasting and inventory management.

Financial Trajectory & Investment Outlook

Revenue Projections

  • The amino acids market exhibits a robust CAGR of over 7%, driven by nutritional and biotech applications.
  • Mineral salts like magnesium chloride and potassium phosphate are expected to grow moderately, with CAGR around 4-6% owing to their widespread use and steady demand.
  • Sodium acetate and sodium chloride maintain high volume sales, supporting stable revenue streams.

Profitability & Investment Opportunities

  • Premium Segment: Bio-based, pharmaceutical-grade amino acids command higher margins, presenting lucrative investment avenues.
  • Diversification: Companies diversifying across multiple compounds mitigate risks associated with raw material shortages.
  • R&D Focus: Investment in innovative, sustainable production processes creates competitive advantage.

Risks & Mitigation

  • Supply Chain Disruption: Diversification of sourcing regions and supplier relationships minimizes risks.
  • Price Volatility: Strategic inventory management and forward contracting stabilize costs.
  • Regulatory Changes: Engagement with regulatory bodies ensures compliance and reduces market entry barriers.

Strategic Outlook

The market for these pharmaceutical chemicals is poised for steady growth driven by technological innovation, demographic shifts, and expanding pharmaceutical R&D portfolios. Companies that invest in sustainable sourcing, quality enhancement, and diversified product lines will be better positioned to capitalize on emerging opportunities.

Key Takeaways

  • The amino acids market is projected to grow rapidly at over 7% CAGR, driven by nutritional and biotech applications.
  • Mineral salts like magnesium chloride and potassium phosphate exhibit steady growth trajectories, supported by their vital roles in clinical nutrition.
  • Sodium acetate and sodium chloride remain staples with high volume demand, but face competitive and sustainability challenges.
  • Supply chain resilience, regulatory compliance, and sustainable sourcing are critical factors influencing future profitability.
  • Strategic R&D and diversification offer pathways for companies to withstand market uncertainties and maximize financial performance.

FAQs

  1. What factors are driving the demand for amino acids in the pharmaceutical industry?
    Increasing R&D in personalized medicines, rising demand for nutritional supplements, and expanded therapeutic applications are primary drivers boosting amino acids consumption.

  2. How does regulation impact the market for mineral salts like magnesium chloride?
    Stringent quality standards and safety regulations necessitate high compliance, which can increase production costs but elevate product quality and market trust.

  3. What are the sustainability considerations in sourcing these chemicals?
    Natural mineral deposits face environmental scrutiny; adopting bio-based extraction and recycling methods can mitigate ecological impact and meet regulatory expectations.

  4. Which regions are leading the market for these compounds?
    North America and Europe dominate due to advanced healthcare infrastructure and stringent quality standards. Asia-Pacific is emerging as a significant growth hub owing to manufacturing capacity expansion.

  5. What are the main risks to these markets' financial trajectories?
    Raw material supply disruptions, regulatory changes, competitive pricing pressures, and environmental challenges could impact revenue growth and margins.

References

[1] Grand View Research, "Amino Acids Market Size, Share & Trends Analysis Report." 2022.
[2] MarketsandMarkets, "Magnesium Chloride Market by Application & Region." 2023.
[3] Transparency Market Research, "Potassium Phosphate Dibasic Market." 2022.
[4] Reports and Data, "Sodium Acetate Market Forecast." 2023.
[5] Research and Markets, "Global Sodium Chloride Market." 2023.

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