Drugs in ATC Class B05B

Up to Top Level ATC Classes

Up to B - Blood and blood forming organs

Up to B05 - BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS

Subclasses in ATC: B05B - I.V. SOLUTIONS

B05BA - Solutions for parenteral nutrition

B05BC - Solutions producing osmotic diuresis

B05B Market Analysis and Financial Projection

Last updated: March 23, 2025

The global market for ATC Class B05B I.V. solutions demonstrates robust growth driven by evolving healthcare needs and technological advancements, while its patent landscape reveals concentrated innovation and competitive pressures. Below is a detailed analysis:

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Market Dynamics

Current Market Size and Projections

• The global IV solutions market was valued at $15.6B in 2024, with projections to reach $23.3B by 2033 (CAGR: 4.53%)[8]. Other estimates suggest a higher CAGR of 8.2%, aiming for $28.8B by 2033[12][15].
• Veterinary IV solutions are growing at 8.1% CAGR, expected to reach $1.62B in 2025[3].

Key Drivers

1. Aging Population: Over 2.1B people aged 60+ by 2050 boost demand for IV hydration and nutrient support[8][12].
2. Chronic Disease Burden: Non-communicable diseases (NCDs) cause 74% of global deaths, necessitating IV therapies for chemotherapy, dialysis, and critical care[8][15].
3. Surgical Procedures: Post-operative fluid management drives volume expander usage (e.g., crystalloids like saline solutions)[9].

Restraints

• Regulatory Hurdles: Strict quality and safety standards increase development costs and delay market entry[12].
• Cost of Maintenance: Sterility requirements and specialized storage escalate operational expenses[15].

Emerging Opportunities

• Home-Based Infusion Therapy: Demand for remote IV administration is rising due to cost efficiency and patient preference[12].
• Drug Delivery Innovations: Smart sensors (e.g., ivWatch’s optical monitors) and nanotechnology enhance precision[4][16].

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Patent Landscape

Key Players and Innovation

• ivWatch dominates IV monitoring with 39+ global patents, including:
  • Optical sensors for early infiltration detection (EP3545827, JP6791826)[4].
  • Motion-adaptive systems to reduce false alarms[16][17].
• Other Trends:
  • Cross-Class Patenting: Companies use ATC codes (e.g., B05B and B05X) to claim broader technical fields, improving strategic positioning[2][5].
  • Telemedicine Integration: Patents increasingly cover remote monitoring systems for IV therapy[4][12].

Challenges in Patent Validity

• PTAB Invalidation Rates: 71% of challenged U.S. patents were fully invalidated in 2024, up from 55% in 2019, raising risks for patent holders[10].
• Global Competition: ivWatch’s expansion into Europe and Japan highlights the need for multi-regional patent portfolios[17].

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Market Segmentation

Category	Leading Segments	Market Share
Product Type	Crystalloids (e.g., saline, dextrose)	>50%[9]
End-User	Hospitals & Clinics	~80%[12]
Geography	North America (U.S. dominance)	35-40%[15]

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Regulatory and Competitive Insights

• Top Manufacturers: Baxter International, B. Braun Medical, and ICU Medical control ~75% of the U.S. market[9].
• Regional Growth: Asia-Pacific shows highest CAGR due to healthcare infrastructure development[15].
• Classification Systems: ATC codes (e.g., B05B for I.V. solutions) guide R&D strategies by defining therapeutic boundaries[13][14].

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“We are committed to bringing products to market that are critical in keeping us all safe from preventable harm.”
— Gary Warren, CEO of ivWatch[4]

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Future Outlook: The IV solutions market will prioritize home-based care technologies and AI-driven delivery systems, while patent strategies focus on global filings and cross-class innovation to mitigate invalidation risks[12][17].

References

1. https://eijppr.com/storage/models/article/5V48DMj2oIDIWTsUKfFWBTiT8YzOvSj6XhVomQdei0ZYmjI1KuMXdlnnCorj/medicines-for-local-therapy-of-wounds-in-the-ukrainian-pharmaceutical-market.pdf
2. https://pmc.ncbi.nlm.nih.gov/articles/PMC10128997/
3. https://www.thebusinessresearchcompany.com/report/veterinary-intravenous-iv-solutions-global-market-report
4. https://www.ivwatch.com/2021/01/21/expanding-the-limits-of-iv-site-monitoring-ivwatch-secures-four-new-patents-globally/
5. https://www.acclaimip.com/patent-landscaping/patent-landscape-analysis-uncovering-strategic-insights/
6. https://s-space.snu.ac.kr/bitstream/10371/152010/1/000000154348.pdf
7. https://www.wipo.int/edocs/pubdocs/en/wipo_pub_941_2017.pdf
8. https://www.imarcgroup.com/intravenous-solutions-market-statistics
9. https://www.ibisworld.com/united-states/industry/intravenous-iv-solution-manufacturing/4107/
10. https://ipwatchdog.com/2024/06/25/recent-statistics-show-ptab-invalidation-rates-continue-climb/id=178226/
11. https://core.ac.uk/download/68788.pdf
12. https://market.us/report/intravenous-solutions-market/
13. https://atcddd.fhi.no/atc_ddd_index/?code=b05
14. https://en.wikipedia.org/wiki/ATC_code_B05
15. https://www.researchandmarkets.com/report/iv-solution
16. https://www.biospace.com/ivwatch-continues-to-expand-global-patent-portfolio
17. https://www.businesswire.com/news/home/20200122005656/en/ivWatch-Bolsters-Intellectual-Property-and-Trademark-Portfolios-Globally