Investigational Drug Information for ONC201
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What is the drug development status for ONC201?
ONC201 is an investigational drug.
There have been 27 clinical trials for ONC201.
The most recent clinical trial was a Phase 2 trial, which was initiated on November 1st 2022.
The most common disease conditions in clinical trials are Glioma, Glioblastoma, and Endometrial Neoplasms. The leading clinical trial sponsors are Oncoceutics, Inc., Chimerix, and National Cancer Institute (NCI).
There are fourteen US patents protecting this investigational drug and one hundred and eighty-one international patents.
Summary for ONC201
| US Patents | 14 |
| International Patents | 181 |
| US Patent Applications | 56 |
| WIPO Patent Applications | 11 |
| Japanese Patent Applications | 3 |
| Clinical Trial Progress | Phase 2 (2022-11-01) |
| Vendors | 67 |
Recent Clinical Trials for ONC201
| Title | Sponsor | Phase |
|---|---|---|
| Testing ONC201 to Prevent Colorectal Cancer | National Cancer Institute (NCI) | Phase 1 |
| ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) | Chimerix | Phase 3 |
| ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer | Genentech, Inc. | Phase 1 |
Clinical Trial Summary for ONC201
Top disease conditions for ONC201
Top clinical trial sponsors for ONC201
US Patents for ONC201
| Drugname | Patent Number | Patent Title | Patent Assignee | Estimated Expiration |
|---|---|---|---|---|
| ONC201 | ⤷ Try a Trial | 7-benzyl-4-(methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]- pyrimidin-5 (1h)-one, salts thereof and methods of using the same in combination therapy | Oncoceutics, Inc. (Philadelphia, PA) | ⤷ Try a Trial |
| ONC201 | ⤷ Try a Trial | Imipridones for gliomas | Oncoceutics, Inc. (Philadelphia, PA) | ⤷ Try a Trial |
| ONC201 | ⤷ Try a Trial | 7-Benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo [1,2-A]pyrido[3,4-E]pyrimidin-5(1H)-one, analogs thereof, and salts thereof and methods for their use in therapy | Oncoceutics, Inc. (Philadelphia, PA) | ⤷ Try a Trial |
| ONC201 | ⤷ Try a Trial | Imipridones for gliomas | Oncoceutics, Inc. (Philadelphia, PA) | ⤷ Try a Trial |
| ONC201 | ⤷ Try a Trial | 7-benzyl-4-(methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-A]pyrido[3,4-E]- pyrimidin-5 (1H)-one, salts thereof and methods of using the same in combination therapy | Oncoceutics, Inc. (Philadelphia, PA) | ⤷ Try a Trial |
| ONC201 | ⤷ Try a Trial | Methods of cancer treatment | K-Gen, Inc. (Burlingame, CA) | ⤷ Try a Trial |
| ONC201 | ⤷ Try a Trial | Small molecule trail gene induction by normal and tumor cells as an anticancer therapy | The Penn State Research Foundation (University Park, PA) | ⤷ Try a Trial |
| >Drugname | >Patent Number | >Patent Title | >Patent Assignee | >Estimated Expiration |
International Patents for ONC201
| Drugname | Country | Document Number | Estimated Expiration | Related US Patent |
|---|---|---|---|---|
| ONC201 | Australia | AU2014244117 | 2033-03-13 | ⤷ Try a Trial |
| ONC201 | Australia | AU2014349150 | 2033-03-13 | ⤷ Try a Trial |
| ONC201 | Australia | AU2019201896 | 2033-03-13 | ⤷ Try a Trial |
| ONC201 | Australia | AU2020200875 | 2033-03-13 | ⤷ Try a Trial |
| ONC201 | Australia | AU2020233606 | 2033-03-13 | ⤷ Try a Trial |
| ONC201 | Australia | AU2022203043 | 2033-03-13 | ⤷ Try a Trial |
| ONC201 | Brazil | BR112015023256 | 2033-03-13 | ⤷ Try a Trial |
| >Drugname | >Country | >Document Number | >Estimated Expiration | >Related US Patent |
