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Last Updated: April 26, 2024

CLINICAL TRIALS PROFILE FOR ONC201

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Clinical Trials for ONC201

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT02038699 ↗	A First-in-man Phase I/II Study of Oral ONC201 in Patients With Advanced Cancer	Withdrawn	Chimerix	Phase 1/Phase 2	ONC201 is a new potential drug that kills cancer cells but not normal cells in laboratory studies. This clinical trial will be the first evaluation of ONC201 in humans and will enroll patients with advanced cancer. This trial includes a phase I portion that will evaluate the safety of ONC201 and the recommended dose for the phase II portion. The phase II portion will evaluate the initial efficacy profile of ONC201 in select types of cancer.
NCT02038699 ↗	A First-in-man Phase I/II Study of Oral ONC201 in Patients With Advanced Cancer	Withdrawn	Oncoceutics, Inc.	Phase 1/Phase 2	ONC201 is a new potential drug that kills cancer cells but not normal cells in laboratory studies. This clinical trial will be the first evaluation of ONC201 in humans and will enroll patients with advanced cancer. This trial includes a phase I portion that will evaluate the safety of ONC201 and the recommended dose for the phase II portion. The phase II portion will evaluate the initial efficacy profile of ONC201 in select types of cancer.
NCT02250781 ↗	Oral ONC201 in Treating Patients With Advanced Solid Tumors	Completed	National Cancer Institute (NCI)	Phase 1	This phase I trial studies the side effects and best dose of Oral ONC201 in treating patients with advanced solid tumors. Oral ONC201 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for ONC201

Condition Name

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Condition Name for
Intervention	Trials
Glioblastoma	3
Diffuse Intrinsic Pontine Glioma	3
Multiple Myeloma	3
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Condition MeSH

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Condition MeSH for
Intervention	Trials
Glioma	7
Glioblastoma	5
Endometrial Neoplasms	4
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Clinical Trial Locations for ONC201

Trials by Country

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Trials by Country for
Location	Trials
United States	46
France	1
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Trials by US State

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Trials by US State for
Location	Trials
California	6
Pennsylvania	5
Michigan	4
New York	4
Texas	4
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Clinical Trial Progress for ONC201

Clinical Trial Phase

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Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 3	2
Phase 2	10
Phase 1/Phase 2	6
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Clinical Trial Status

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Clinical Trial Status for
Clinical Trial Phase	Trials
Recruiting	8
Active, not recruiting	4
Completed	4
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Clinical Trial Sponsors for ONC201

Sponsor Name

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Sponsor Name for
Sponsor	Trials
Oncoceutics, Inc.	15
Chimerix	10
National Cancer Institute (NCI)	7
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Sponsor Type

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Sponsor Type for
Sponsor	Trials
Other	30
Industry	27
NIH	7
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