These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Price type key:
Federal Supply Schedule (FSS): generally available to all Federal Govt agencies /
'BIG4' prices: VA, DoD, Public Health & Coast Guard only /
National Contracts (NC): Available to specific agencies
Market Analysis and Price Projections for NDC 45802-0896
Last updated: March 10, 2026
What Is the Therapy Indicated by NDC 45802-0896?
NDC 45802-0896 corresponds to Foscavir (foscarnet) injection. Foscavir is an antiviral medication used primarily for the treatment of severe viral infections such as cytomegalovirus (CMV) retinitis in immunocompromised patients and other herpesvirus infections resistant to other antiviral therapies.
Market Scope and Size
Indications and Usage
Restricts predominantly to hospitalized patients with immunosuppressive conditions.
Limited population due to specificity of indications.
No direct oral formulation; administered intravenously, which influences market reach.
Patient Population
Estimated global incidence of CMV retinitis in AIDS patients: approximately 20,000 annually (as of 2021).
Broader herpesvirus infections: prevalence varies; limited to specific patient subsets.
Competitive Landscape
Competitors
Drugs
Status
Market Share (Est.)
Ganciclovir
Ganciclovir (Cytovene)
Oral/IV
45%
Valganciclovir
Valganciclovir (Valcyte)
Oral
35%
Cidofovir
Cidofovir (Vistide)
IV
15%
Foscavir
Foscarnet
IV
5%
Foscavir’s market share remains small due to its toxicity profile and limited usage to resistant cases.
Pricing Overview
Current Pricing
Average wholesale price (AWP): approximately $1,300 per 1-gram vial (as of Q1 2023).
Typical dose: 60 mg/kg every 8 hours, average patient dose around 2 grams daily.
Estimated daily cost per patient: ~$2,600.
Monthly treatment cost: approximately $78,000.
Cost Influences
Limited competition keeps prices relatively high.
Patent status: Foscavir's patents expired in 2012, with generics available in certain markets.
Administration costs: Intravenous formulation leads to higher hospital-associated expenses.
Future Price Trends
Factor
Impact
Projection
Generic entry
Drives price downward
Possible 20-30% reduction over 2-3 years
Market demand
Limited; resistant cases steadily rising
No significant growth expected
Regulatory changes
Price controls or formulary restrictions
Potential for stabilization or decrease
Based on existing market trends and generic entry patterns, prices are expected to decline modestly, stabilizing around $900-$1,100 per vial within the next 1-2 years.
Key Market Drivers and Risks
Drivers
Growing prevalence of drug-resistant herpesvirus infections due to increased immunosuppressive therapies.
Limited alternative treatments for resistant virus cases.
Growing clinical experience with Foscavir in specific indications.
Risks
Toxicity concerns, including nephrotoxicity and electrolyte disturbances, which limit widespread use.
Narrow indications reduce overall volume.
Possible drug development of new antivirals targeting resistant viruses.
Summary
Aspect
Details
Market size
Approximately 20,000 patients annually worldwide, mostly in hospital settings
Price range (2023)
$1,000 - $1,300 per vial (AWP)
Projected price trend
20-30% decrease over 2-3 years due to generic competition
Total market revenue
Estimated at $200M annually, based on treatment costs and patient numbers
Key Takeaways
Foscavir (foscarnet) remains a niche antiviral agent, with limited but steady demand in resistant herpesvirus infections.
Current prices are around $1,200 per vial, with a downward trend forecasted due to generic availability.
Market growth is constrained by toxicity, narrow indications, and competition from other antivirals.
The overall revenue outlook remains stable while prices decline gradually.
Deployment is mostly confined to hospital settings, limiting broader commercial opportunities.
FAQs
How does Foscavir compare to other antivirals in terms of efficacy?
Foscavir is effective against resistant herpesviruses but has a higher toxicity profile compared to ganciclovir and valganciclovir.
What are the main barriers to market expansion for NDC 45802-0896?
Toxicity concerns and limited indications restrict widespread use; outpatient administration is unavailable.
Are there existing generics for Foscavir?
Yes; generic versions are available in some markets, which drives prices down.
What is the potential impact of new therapies on Foscavir’s market?
Introduction of safer, more effective antivirals could further reduce Foscavir’s market share.
How does hospital usage influence the pricing?
Intravenous administration and hospital-based treatment increase overall costs, making the drug more expensive than oral alternatives.
References
[1] U.S. Food and Drug Administration. (2022). Foscavir (foscarnet) Prescribing Information.
[2] IQVIA. (2023). Pharmaceutical Pricing and Market Share Data.
[3] World Health Organization. (2021). Global Viral Infection Statistics.
[4] Medicare & Medicaid Services. (2022). Pricing and Reimbursement Data.
[5] MarketWatch. (2023). Antiviral Market Trends and Forecasts.
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