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Last Updated: January 21, 2025

PENTACEL Drug Profile


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Summary for Tradename: PENTACEL
High Confidence Patents:0
Applicants:1
BLAs:1
Recent Clinical Trials: See clinical trials for PENTACEL
Recent Clinical Trials for PENTACEL

Identify potential brand extensions & biosimilar entrants

SponsorPhase
The Hospital for Sick ChildrenPhase 4

See all PENTACEL clinical trials

Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

  1. Brand-side disclosures in response to biosimilar applications
  2. These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

  3. General brand-side disclosures
  4. These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

  5. Patents from broad patent text search
  6. For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for PENTACEL Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for PENTACEL Derived from Company Disclosures

No patents found based on company disclosures

3) Low Certainty: US Patents for PENTACEL Derived from Patent Text Search

No patents found based on company disclosures

Market Dynamics and Financial Trajectory for the Biologic Drug: Pentacel

Introduction

Pentacel, a combination vaccine developed by Sanofi, is designed to protect against diphtheria, tetanus, pertussis (whooping cough), and Haemophilus influenzae type b (Hib). This vaccine is a crucial component of pediatric vaccination schedules globally. Here, we will delve into the market dynamics and financial trajectory of Pentacel.

Global Vaccine Market Overview

The global vaccine market is experiencing significant growth driven by ongoing global immunization efforts, expansion of vaccination programs, and increased research and development initiatives. The pentavalent vaccine market, which includes Pentacel, is expected to grow steadily in the coming years, driven by these factors[3].

Market Size and Growth

The pentavalent vaccine market, which includes vaccines like Pentacel, is projected to grow from $2.53 billion in 2023 to $2.65 billion in 2024, and further to $3.17 billion by 2028 at a compound annual growth rate (CAGR) of 4.6%. This growth is attributed to global health initiatives, public awareness campaigns, and technological innovations in vaccine manufacturing[3].

Competitive Landscape

In the competitive landscape of vaccines, Pentacel competes with other combination vaccines such as Pentaxim and Hexaxim, also developed by Sanofi. These vaccines are popular in various regions, including China, where they account for a significant market share. For instance, in China's vaccine market, Pentacel and similar vaccines from Sanofi hold a notable position, particularly in the DTP and Hib vaccine segments[4].

Regional Market Dynamics

China

In China, the DTP vaccine market, which includes Pentacel, is expected to reach RMB 8.6 billion by 2030, growing at a CAGR of 12.6% from RMB 1.9 billion in 2017. This growth is driven by government policies, regulatory frameworks, and public awareness campaigns[4].

Global

Globally, the demand for pentavalent vaccines is increasing due to their convenience and comprehensive protection against multiple diseases. This trend is supported by global health organizations and funding initiatives aimed at expanding vaccination programs into new geographies[3].

Financial Performance of Sanofi

Sanofi, the manufacturer of Pentacel, has seen significant growth in its vaccine segment. In Q2 2021, Sanofi's vaccine sales increased by 16.2%, driven by the recovery of the meningitis and boosters franchise, as well as the acceleration of its mRNA pipeline. This growth indicates a strong financial performance for Sanofi's vaccine division, which includes Pentacel[5].

Impact of Global Events

COVID-19 Pandemic

The COVID-19 pandemic has had a mixed impact on the vaccine market. While it disrupted some supply chains and economic recoveries, it also accelerated the development and distribution of vaccines. For Pentacel, the pandemic may have led to temporary disruptions but also highlighted the importance of vaccination programs, potentially boosting long-term demand[1].

Russia-Ukraine War

The Russia-Ukraine war has caused economic sanctions, commodity price surges, and supply chain disruptions, affecting various markets globally. However, the vaccine market, including pentavalent vaccines like Pentacel, is expected to remain resilient due to its essential nature and ongoing global health initiatives[1].

Key Trends and Drivers

Global Health Initiatives

Global health initiatives and funding play a crucial role in driving the demand for pentavalent vaccines. Organizations like the World Health Organization (WHO) and UNICEF support vaccination programs, which in turn boost the sales of vaccines like Pentacel[3].

Technological Innovations

Technological innovations in vaccine manufacturing are improving the efficacy, safety, and accessibility of vaccines. These advancements are expected to further drive the growth of the pentavalent vaccine market[3].

Public Awareness and Education

Public awareness and education campaigns are vital in increasing vaccination rates. These campaigns help in reducing vaccine hesitancy and increasing the demand for vaccines like Pentacel[3].

Challenges and Opportunities

Supply Chain Disruptions

Supply chain disruptions, such as those caused by the COVID-19 pandemic and the Russia-Ukraine war, can impact the availability of vaccines. However, manufacturers like Sanofi are working to mitigate these risks through diversified supply chains and strategic partnerships[1].

Regulatory Frameworks

Government policies and regulatory frameworks can significantly influence the vaccine market. Favorable policies can accelerate the approval and distribution of vaccines, while stringent regulations can pose challenges[3].

Conclusion

The market dynamics for Pentacel are favorable, driven by global health initiatives, technological innovations, and public awareness campaigns. Despite challenges such as supply chain disruptions, the financial trajectory for Pentacel and similar vaccines is expected to be positive.

Key Takeaways

  • The pentavalent vaccine market, including Pentacel, is projected to grow at a CAGR of 4.6% from 2023 to 2028.
  • Global health initiatives and funding are key drivers of the market.
  • Technological innovations in vaccine manufacturing are improving vaccine efficacy and accessibility.
  • Public awareness and education campaigns are crucial in increasing vaccination rates.
  • Supply chain disruptions and regulatory frameworks can impact the market but are being mitigated by manufacturers.

FAQs

What is Pentacel?

Pentacel is a combination vaccine developed by Sanofi that protects against diphtheria, tetanus, pertussis (whooping cough), and Haemophilus influenzae type b (Hib).

What is the projected growth rate of the pentavalent vaccine market?

The pentavalent vaccine market is expected to grow at a CAGR of 4.6% from 2023 to 2028[3].

How does the COVID-19 pandemic affect the vaccine market?

The COVID-19 pandemic has caused temporary disruptions but also highlighted the importance of vaccination programs, potentially boosting long-term demand for vaccines like Pentacel[1].

What are the key drivers of the pentavalent vaccine market?

Key drivers include global health initiatives, technological innovations in vaccine manufacturing, and public awareness and education campaigns[3].

What challenges does the vaccine market face?

The vaccine market faces challenges such as supply chain disruptions and stringent regulatory frameworks, but manufacturers are working to mitigate these risks[1][3].

Sources

  1. PR Newswire: DTP Vaccines Global Market Report 2023
  2. Biospace: Pfizer Reports Strong Third-Quarter 2024 Results And Raises 2024 Guidance
  3. GII Research: Pentavalent Global Market Report 2024
  4. Mirae Asset Global Investments: China's Vaccine Market Dynamics
  5. Sanofi: Sales growth accelerated - Full-year guidance raised - Q2 2021

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