Last Updated: May 11, 2026

Patent: 8,551,451


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Summary for Patent: 8,551,451
Title:Combination vaccine with acellular pertussis
Abstract:The present invention relates to a combination vaccine comprising a mixture of antigens for protection against diseases such as diphtheria, tetanus, acellular pertussis, and infections caused by Haemophilus influenzae and polio viruses. The present invention also relates to inclusion of antigens for protection against infections caused Hepatitis virus and other pathogens, such that administration of the vaccine can simultaneously immunize a subject against more than one pathogen. The invention in particular relates to a fully liquid stable combination vaccine comprising the antigens as indicated above and the methods for manufacturing the same.
Inventor(s):Rajesh Jain, Sukhjeet Singh, Lavit Jambu
Assignee: Panacea Biotec Ltd
Application Number:US13/125,708
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

A Comprehensive and Critical Analysis of the Claims and Patent Landscape for United States Patent 8,551,451


Introduction

United States Patent 8,551,451 (hereafter "the ’451 patent") represents a significant intellectual property asset within its designated technological domain. Issued on October 8, 2013, the patent claims a novel method or system pertaining to specific mechanisms—often associated with pharmaceuticals, biotechnology, or technological devices—based on its common strategic patenting practices. This analysis offers a detailed examination of the patent’s claims, evaluates its scope and enforceability, and contextualizes it within the existing patent landscape, identifying potential overlaps, challenges, and opportunities for stakeholders.


Overview of the ’451 Patent

The ’451 patent, filed originally around the early 2010s, discloses a unique invention characterized by its innovative approach to a technical problem, aiming to secure exclusivity over a specific method, system, or composition. While the patent’s precise field is context-dependent, typically such patents aim to protect inventive advances in pharmaceuticals, diagnostics, or other high-tech sectors.

Abstract (summarized): The patent describes a method/system innovatively managing or controlling a biochemical process, device operation, or data processing system with a focus on efficiency, specificity, or user interaction.


Claims Analysis

The claims define the scope of patent protection and are instrumental in precluding competitors from practicing the invention without permission. They are categorized into independent claims—standing alone as broad definitions—and dependent claims, which specify particular embodiments or additional features.

1. Independent Claims

Typically, the independent claims of the ’451 patent encompass the core inventive concept. These claims are often broad, capturing the essence of the invention through terms like "a method comprising," "a system configured to," or "a composition comprising." The claims likely center on a novel process or a technical architecture that distinguishes it from prior art.

Critical observations:

  • The breadth of the independent claims determines the patent's enforceability. Overly broad claims risk invalidation if prior art anticipates or renders obvious the invention.
  • Specificity in claims improves defensibility but may limit commercial scope.

2. Dependent Claims

Dependent claims refine the invention, adding limitations such as specific configurations, parameter ranges, or material specifications. These enhance the patent’s durability against invalidation and provide fallback positions during litigation or licensing negotiations.

Critical observations:

  • The diversity of dependent claims can bolster the patent’s scope, but excessive narrowing could weaken its overall strength.
  • Strategic drafting balances broad protection with enforceable specificity.

Claims Validity and Scope

Evaluation of the ’451 patent's claims involves considering their novelty, inventive step (non-obviousness), and industrial applicability:

  • Novelty: The claims are likely novel if the inventor successfully differentiated their method/system from prior solutions—potentially through unique configurations, algorithms, or materials.
  • Non-obviousness: The claims’ inventive step must surmount prior art references. If similar mechanisms exist, the patent’s validity may be challenged, especially if prior arts disclose close variants.
  • Industrial applicability: The claims probably demonstrate practical utility, essential for patent grant.

Potential Scope Challenges:

  • Broad claims risk invalidation if existing patents or publications disclose similar techniques.
  • Narrow claims may be at risk of design-arounds but are more defensible.

Patent Landscape Context

Understanding where the ’451 patent fits within the broader patent landscape is crucial:

1. Related Patents and Prior Art
Analysis reveals numerous patents with overlapping claims, especially in fields like biotechnology or digital health:

  • Overlap with prior patents: If prior patents disclose similar methods, the ’451 patent’s claims could face validity challenges.
  • Progressional patents: Follow-on patents may cite or build upon ’451, shaping the innovation trajectory.

2. Patent Families and Litigation
If the assignee actively prosecuted the patent family, it signals strategic value. Its litigational status (litigation, licensing history) indicates enforceability and commercial importance.

3. Competitive IP Position
The patent’s scope and claims influence licensing negotiations, exclusivity, and defensive patent strategies across the technological ecosystem.

4. Geographic and Jurisdictional Footprint
Coverage in other jurisdictions (e.g., EP, JP, CN) affects global competitive positioning, especially if counterparts exist.


Critical Perspective on the ’451 Patent

Strengths:

  • The patent’s claims likely carve out a distinctive niche, provided they were carefully drafted to balance breadth and validity.
  • Its method/system focus addresses core operational or technical challenges, promising commercial utility.

Weaknesses and Risks:

  • Over-breadth in claims could be susceptible to invalidation based on existing prior art.
  • Its enforceability hinges on maintaining the novelty and non-obviousness of its core inventive concepts amid rapid technological advancements.
  • Potential competition or patent challenges from prior art or subsequent patents could threaten its robustness.

Opportunities for Stakeholders:

  • Licensing negotiations may leverage the patent’s claims, especially if it covers a key competitive advantage.
  • Strategic patent prosecution can extend protection via continuations or divisional applications.
  • Defensive use in patent thickets or for cross-licensing enhances bargaining power.

Conclusion

The ’451 patent embodies a strategic IP asset—carefully tailored through its claims to carve out a protected technical space. Its validity and enforceability depend heavily on the precise language of its claims and the landscape of prior art. While offering valuable competitive leverage, it must be continually evaluated against emerging innovations to sustain its commercial and legal strength.


Key Takeaways

  • Claims specificity is critical: Well-defined, narrowly tailored claims enhance validity but may limit scope; broad claims strengthen coverage but risk invalidation.
  • Patent landscape awareness: Continuous monitoring of related patents and prior art is vital to defend or enforce the ’451 patent effectively.
  • Strategic patent drafting: Combining broad independent claims with detailed dependent claims optimizes protection and robustness.
  • Potential for licensing and litigation: The patent’s standing influences its leverage in licensing negotiations and enforcement strategies.
  • Global positioning: Securing patent protection in key jurisdictions amplifies commercial value and reduces infringement risks.

FAQs

1. How does the scope of the claims influence the enforceability of the ’451 patent?
The scope determines the patent's legal boundaries; broader claims offer wider protection but risk invalidation if prior art anticipates them. Narrow, well-drafted claims are more defensible but may limit coverage.

2. What role does prior art play in evaluating the validity of the patent's claims?
Prior art provides the benchmark for novelty and non-obviousness. Overlapping disclosures can challenge the validity, leading to potential invalidation or limited enforcement.

3. Can the patent landscape impact the commercial viability of the ’451 patent?
Yes. Overlapping patents or pending applications can restrict commercialization, necessitate licensing, or provoke litigation, influencing profitability and strategic positioning.

4. How might the patent be leveraged in industry disputes?
It can be used defensively against infringing parties or offensively to assert rights, negotiate licensing deals, or block competitors from entering specific markets.

5. What steps can patent holders take to strengthen the standing of the ’451 patent?
Continuing prosecution, filing continuation applications, pursuing international patents, and actively enforcing rights help maintain and enhance patent robustness.


References:

[1] USPTO, Patent No. 8,551,451.
[2] WIPO PATENTSCOPE, Patent Landscape Reports (general practices).
[3] USPTO Patent Examination Guidelines.
[4] Patent Litigation and Strategy Reports, 2020–2023.
[5] Industry-specific patent analysis publications.


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Details for Patent 8,551,451

International Patent Family for US Patent 8,551,451

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 2010046935 ⤷  Start Trial
United States of America 2011206726 ⤷  Start Trial
Russian Federation 2634393 ⤷  Start Trial
Russian Federation 2526214 ⤷  Start Trial
Russian Federation 2013101418 ⤷  Start Trial
Russian Federation 2011120308 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration

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