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BOTOX Drug Profile

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Summary for Tradename: BOTOX

Patents:	34
Applicants:	1
BLAs:	1
Suppliers: see list	1
Drug Prices:	Drug price information for BOTOX
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for BOTOX

Pharmacology for BOTOX

Mechanism of Action

Acetylcholine Release Inhibitors

US Patents for BOTOX

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Patent Expiration	Status	Orphan	Source
Allergan	BOTOX	onabotulinumtoxina	VIAL; SINGLE-USE	103000	001	1991-12-09		SIO2 MEDICAL PRODUCTS, INC. (Auburn, AL)		RX		search
Allergan	BOTOX	onabotulinumtoxina	VIAL; SINGLE-USE	103000	001	1991-12-09		NANOMED SKINCARE, INC. (Cupertino, CA)		RX		search
Allergan	BOTOX	onabotulinumtoxina	VIAL; SINGLE-USE	103000	001	1991-12-09		Allergan, Inc. (Irvine, CA)		RX		search
Allergan	BOTOX	onabotulinumtoxina	VIAL; SINGLE-USE	103000	001	1991-12-09		The Regents of the University of Colorado (Boulder, CO)		RX		company
Allergan	BOTOX	onabotulinumtoxina	VIAL; SINGLE-USE	103000	001	1991-12-09		Allergan, Inc. (Irvine, CA)		RX		company
Allergan	BOTOX	onabotulinumtoxina	VIAL; SINGLE-USE	103000	001	1991-12-09		Allergan, Inc. (Irvine, CA)		RX		company

International Patents for BOTOX

Country	Document Number	Estimated Expiration
Portugal	1502601
China	1321683
Japan	2008538201
European Patent Office	1072270
European Patent Office	2200528
Taiwan	I377074

Supplementary Protection Certificates for BOTOX

Supplementary Protection Certificate	SPC Country	SPC Expiration	SPC Description
92250	Luxembourg		PRODUCT NAME: TOXINE BOTULIQUE DE TYPE A DE CLOSTRIDIUM BOTULINUM
C02145629/01	Switzerland		FORMER OWNER: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE, US
SPC/GB13/078	United Kingdom		PRODUCT NAME: BOTULINUM TOXIN TYPE A; REGISTERED: FI 263103-5/2012 20130116; UK PL 00426/0118 - 0061 20130904; UK PL 00426/0074 - 0139 20130904; UK PL 00426/0119 - 0047 20130904
C01658858/01	Switzerland		FORMER OWNER: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE, US
C300564	Netherlands		PRODUCT NAME: BOTULINUM TOXINE; NAT. REGISTRATION NO/DATE: RVG 32957RVG 17379RVG 32958 2012270627; FIRST REGISTRATION: NL 25449 20110822
2013/025	Ireland		PRODUCT NAME: BOTULINUM TOXIN TYPE A; NAT REGISTRATION NO/DATE: PA0148/060/001 20130117; FIRST REGISTRATION NO/DATE: PA018/060/002 17/01/2013 IRELAND PA0148/060/003 17/01/2013 FINLAND 25162 16/01/2013 FINLAND 15424 16/01/2013 FINLAND 28146 20130116