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Last Updated: April 26, 2024

Patent: 9,321,846


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Summary for Patent: 9,321,846
Title:Compositions and methods comprising binding proteins for adalimumab
Abstract: Compositions and methods comprising proteins that bind specifically to adalimumab are disclosed herein. Adalimumab is a monoclonal antibody specific for the cytokine TNF-.alpha. and was developed to treat TNF-.alpha. mediated inflammatory diseases. In one aspect of the instant invention, the binding proteins are antibodies directed toward adalimumab. These antibodies, including binding fragments thereof, can be used in a clinical setting as well as for research and development. For example, these anti-adalimumab antibodies can be employed to neutralize adalimumab.
Inventor(s): Kaymakcalan; Zehra (Westborough, MA), Xiong; Limin (Shrewsbury, MA)
Assignee: ABBVIE BIOTECHNOLOGY LTD. (Hamilton, BM)
Application Number:14/630,322
Patent Claims:see list of patent claims

Details for Patent 9,321,846

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Abbvie Inc. HUMIRA adalimumab Injection 125057 12/31/2002 ⤷  Try a Trial 2027-08-28
Abbvie Inc. HUMIRA adalimumab Injection 125057 02/21/2008 ⤷  Try a Trial 2027-08-28
Abbvie Inc. HUMIRA adalimumab Injection 125057 04/24/2013 ⤷  Try a Trial 2027-08-28
Abbvie Inc. HUMIRA adalimumab Injection 125057 09/23/2014 ⤷  Try a Trial 2027-08-28
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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