Patent: 5,703,207
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Summary for Patent: 5,703,207
Title: | Protein active in humoral hypercalcemia of malignancy-PTHrP |
Abstract: | A sub-unit or fragment of parathyroid hormone related protein having the following characteristics: (a) an N-terminal amino acid sequence A V S E H Q L L H D K G K S I Q D L R R R F F L H H L I A E I H T A E I R A T S E V S P N; (b) a molecular weight between 15 to 25 kilodaltons, as determined by sodium dodecyl polyacrylamide gel electrophoresis under reducing and non-reducing conditions; and (c) a specific biological activity of at least about 6 mg equivalents of a peptide composed of amino acids 1-34 a parathyroid hormone related protein per mg protein as measured in an adenylate cyclase response assay. |
Inventor(s): | Martin; Thomas J. (Kew, AU), Moseley; Jane M. (North Balwyn, AU), Kemp; Bruce E. (Kew, AU), Wettenhall; Richard E. H. (Camberwell, AU) |
Assignee: | The University of Melbourne (Victoria, AU) |
Application Number: | 08/352,622 |
Patent Claims: | see list of patent claims |
Details for Patent 5,703,207
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Nps Pharmaceuticals, Inc. | NATPARA | parathyroid hormone | For Injection | 125511 | 01/23/2015 | ⤷ Try a Trial | 2014-12-30 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |