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Last Updated: August 12, 2020

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Patent: 9,700,486

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Summary for Patent: 9,700,486
Title:Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
Abstract: The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, GAMMAGARD LIQUID (an immune globulin infusion (human)); ADVATE (Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method, (rAHF)); BAX 111 (vonicog alfa, or [618-threonine,709-aspartic acid] von Willebrand factor Homo sapiens (1381A>T,1472H>D variant)); or an adeno-associated viral vector containing a liver-specific human factor IX expression cassette, e.g., sscAAV2/8-LP1-hFIXco.
Inventor(s): Weeks; Wendell P. (Corning, NY), Schaut; Robert Anthony (Painted Post, NY), DeMartino; Steven Edward (Painted Post, NY), Peanasky; John Stephen (Big Flats, NY)
Assignee: Corning Incorporated (Corning, NY)
Application Number:14/259,273
Patent Claims:see list of patent claims

Details for Patent 9,700,486

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bayer Healthcare Llc KOVALTRY antihemophilic factor (recombinant) KIT 125574 1 2016-03-17   Start Trial Corning Incorporated (Corning, NY) 2033-04-24 search
Octapharma Usa Inc NUWIQ antihemophilic factor (recombinant) KIT 125555 1 2017-08-01   Start Trial Corning Incorporated (Corning, NY) 2033-04-24 search
Novo Nordisk NOVOEIGHT (antihemophilic factor, recombinant) KIT 125466 1 2015-04-01   Start Trial Corning Incorporated (Corning, NY) 2033-04-24 search
Wyeth Biopharma Division Of Wyeth Pharmaceuticals Llc XYNTHA antihemophilic factor (recombinant) KIT 125264 1 2011-08-01   Start Trial Corning Incorporated (Corning, NY) 2033-04-24 search
Baxalta Us Inc. ADVATE antihemophilic factor (recombinant) KIT 125063 1 2011-12-15   Start Trial Corning Incorporated (Corning, NY) 2033-04-24 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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