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Last Updated: June 10, 2023

Patent: 9,643,980

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Summary for Patent: 9,643,980
Title:Benzoxazepin oxazolidinone compounds and methods of use
Abstract: Described herein are benzoxazepin oxazolidinone compounds with phosphoinositide-3 kinase (PI3K) modulation activity or function having the Formula I structure: ##STR00001## or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such PI3K modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon PI3K dysregulation.
Inventor(s): Braun; Marie-Gabrielle (South San Francisco, CA), Hanan; Emily (Redwood City, CA), Staben; Steven T. (San Francisco, CA), Heald; Robert Andrew (Sawbridgeworth, GB), MacLeod; Calum (Harlow Essex, GB), Elliott; Richard (Harlow Essex, GB)
Assignee: Genentech, Inc. (South San Francisco, CA)
Application Number:15/200,307
Patent Claims:see list of patent claims

Details for Patent 9,643,980

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 09/25/1998 ⤷  Try a Trial 2039-02-26
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 02/10/2017 ⤷  Try a Trial 2039-02-26
Genentech, Inc. AVASTIN bevacizumab Injection 125085 02/26/2004 ⤷  Try a Trial 2039-02-26
Genentech, Inc. PERJETA pertuzumab Injection 125409 06/08/2012 ⤷  Try a Trial 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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