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AVASTIN Drug Profile

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Summary for Tradename: AVASTIN

Patents:	760
Applicants:	1
BLAs:	1
Suppliers: see list	1
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for AVASTIN

Pharmacology for AVASTIN

Mechanism of Action

Vascular Endothelial Growth Factor Receptor Inhibitors Vascular Endothelial Growth Factor-directed Antibody Interactions

US Patents for AVASTIN

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Patent Expiration	Status	Orphan	Source
Genentech	AVASTIN	bevacizumab	VIAL; INTRAVENOUS	125085	002	2004-02-26		Genentech, Inc. (South San Francisco, CA)		RX		search
Genentech	AVASTIN	bevacizumab	VIAL; INTRAVENOUS	125085	002	2004-02-26		Bayer Intellectual Property GMBH (Monheim, DE)		RX		search
Genentech	AVASTIN	bevacizumab	VIAL; INTRAVENOUS	125085	002	2004-02-26		THE PENN STATE RESEARCH FOUNDATION (University Park, PA)		RX		search
Genentech	AVASTIN	bevacizumab	VIAL; INTRAVENOUS	125085	002	2004-02-26		Moerae Matrix, Inc. (Morristown, NJ)		RX		search
Genentech	AVASTIN	bevacizumab	VIAL; INTRAVENOUS	125085	002	2004-02-26		EYED PHARMA (Liege, BE)		RX		search
Genentech	AVASTIN	bevacizumab	VIAL; INTRAVENOUS	125085	002	2004-02-26		IMMATICS BIOTECHNOLOGIES GMBH (Tuebingen, DE)		RX		search

International Patents for AVASTIN

Country	Patent Number	Estimated Expiration
New Zealand	587907
China	106188059
South Africa	201405881
Slovenia	2049500
Denmark	2049500
European Patent Office	3129362

Supplementary Protection Certificates for AVASTIN

Supplementary Protection Certificate	SPC Country	SPC Expiration	SPC Description
C300238	Netherlands		PRODUCT NAME: NATALIZUMAB; REGISTRATION NO/DATE: EU/1/06/346/001 20060627
122006000043	Germany		PRODUCT NAME: NATALIZUMAB; NAT. REGISTRATION NO/DATE: EU /1/06/346/001 20060627; FIRST REGISTRATION: EU EU/1/06/346/001 20060627
CA 2015 00006	Denmark		PRODUCT NAME: POMALIDOMID OG FARMACEUTISK ACCEPTABLE SALTE, SOLVATER, HYDRATER ELLER STEREOISOMERER HERAF; REG. NO/DATE: EU/1/13/850 20130805
1590004-6	Sweden		PRODUCT NAME: POMALIDOMIDE AND PHARMACEUTICALLY ACCEPTABLE SALTS, SOLVATES, HYDRATES OR STEREOISOMERS THEREOF; REG. NO/DATE: EU/1/13/850 20130808
PA2014022	Lithuania		PRODUCT NAME: PACLITAXELUM; REGISTRATION NO/DATE: EU/1/07/428/001-002 20131220
00140	Estonia