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Serving 500+ biopharmaceutical companies globally:

Fuji
Fish and Richardson
UBS
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Dow
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Farmers Insurance
Mallinckrodt
McKesson
Colorcon

Generated: September 19, 2017

Patent: ► Subscribe

Summary for Patent: ► Subscribe

Title:Weakly acidic pH-responsive peptide and liposome containing same
Abstract: A problem to be solved by the present invention is to provide a peptide compound for producing a drug delivery carrier capable of releasing a target substance in a weakly acidic pH environment. The present invention provides a peptide compound comprising a hydrophilic amino acid block and a hydrophobic amino acid block; [1] the peptide compound containing 24 to 36 amino acids in total; [2] the hydrophilic amino acid block containing 4 to 10 amino acids in total and having an average hydropathy index of -3.0 to -1.0; and [3] the hydrophobic amino acid block containing 20 to 32 amino acids in total, containing one or more His residues, and having an average hydropathy index of 1.0 to 2.5.
Inventor(s): Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP)
Assignee: Taiho Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:14/430,723
Patent Claim Types:
see list of patent claims
Compound; Dosage form; Composition;

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Inventors Patent Expiration Status Orphan Source
Amgen
NEUPOGEN
filgrastim
VIAL1033530011991-02-20► Subscribe Taiho Pharmaceutical Co., Ltd. (Tokyo, JP) Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP) ► SubscribeRXsearch
Amgen
NEUPOGEN
filgrastim
VIAL1033530021991-02-20► Subscribe Taiho Pharmaceutical Co., Ltd. (Tokyo, JP) Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP) ► SubscribeRXsearch
Amgen
NEUPOGEN
filgrastim
SYRINGE1033530031991-02-20► Subscribe Taiho Pharmaceutical Co., Ltd. (Tokyo, JP) Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP) ► SubscribeRXsearch
Amgen
NEUPOGEN
filgrastim
SYRINGE1033530041991-02-20► Subscribe Taiho Pharmaceutical Co., Ltd. (Tokyo, JP) Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP) ► SubscribeRXsearch
Genentech
RITUXAN
rituximab
VIAL1037050011997-11-26► Subscribe Taiho Pharmaceutical Co., Ltd. (Tokyo, JP) Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP) ► SubscribeRXsearch
Eisai Inc
ONTAK
denileukin diftitox
VIAL1037670011999-02-05► Subscribe Taiho Pharmaceutical Co., Ltd. (Tokyo, JP) Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP) ► SubscribeRXOrphansearch
Genentech
HERCEPTIN
trastuzumab
VIAL; INTRAVENOUS1037920011998-09-25► Subscribe Taiho Pharmaceutical Co., Ltd. (Tokyo, JP) Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP) ► SubscribeRXOrphansearch
Genzyme
CAMPATH
alemtuzumab
VIAL; INTRAVENOUS1039480012001-05-07► Subscribe Taiho Pharmaceutical Co., Ltd. (Tokyo, JP) Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP) ► SubscribeRXOrphansearch
Genzyme
CAMPATH
alemtuzumab
VIAL; INTRAVENOUS1039480022001-05-07► Subscribe Taiho Pharmaceutical Co., Ltd. (Tokyo, JP) Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP) ► SubscribeRXOrphansearch
Genzyme
LEMTRADA
alemtuzumab
INJECTABLE;INJECTION1039480032001-05-07► Subscribe Taiho Pharmaceutical Co., Ltd. (Tokyo, JP) Kogure; Kentaro (Otsu, JP), Hama; Susumu (Otsu, JP) ► SubscribeRXOrphansearch
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Summary for Patent: ► Subscribe

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan2012-233011Oct 22, 2012
PCT Information
PCT FiledOctober 21, 2013PCT Application Number:PCT/JP2013/078497
PCT Publication Date:May 01, 2014PCT Publication Number: WO2014/065245

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Country Document Number Publication Date
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Serving 500+ biopharmaceutical companies globally:

Harvard Business School
Fish and Richardson
US Department of Justice
Dow
Cipla
Daiichi Sankyo
Colorcon
Deloitte
Boehringer Ingelheim
Julphar

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