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Last Updated: September 24, 2020

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Patent: 9,371,377

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Summary for Patent: 9,371,377
Title:Anti-C5 antibodies having improved pharmacokinetics
Abstract: The disclosure provides antibodies that are useful for, among other things, inhibiting terminal complement (e.g., the assembly and/or activity of the C5b-9 TCC) and C5a anaphylatoxin-mediated inflammation and, thus, treating complement-associated disorders. The antibodies have a number of improved properties relative to eculizumab, including, e.g., increased serum half-life in a human.
Inventor(s): Andrien, Jr.; Bruce A. (Guilford, CT), Sheridan; Douglas L. (Branford, CT), Tamburini; Paul P. (Kensington, CT)
Assignee: Alexion Pharmaceuticals, Inc. (New Haven, CT)
Application Number:14/923,879
Patent Claims:see list of patent claims

Details for Patent 9,371,377

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Alexion Pharm ULTOMIRIS ravulizumab-cwvz INJECTABLE;INJECTION 761108 001 2019-10-18   Start Trial Alexion Pharmaceuticals, Inc. (New Haven, CT) 2034-03-07 RX Orphan company
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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