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Last Updated: March 28, 2024

Patent: 9,803,007


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Summary for Patent: 9,803,007
Title:Anti-C5 antibodies having improved pharmacokinetics
Abstract: The disclosure provides antibodies that are useful for, among other things, inhibiting terminal complement (e.g., the assembly and/or activity of the C5b-9 TCC) and C5a anaphylatoxin-mediated inflammation and, thus, treating complement-associated disorders. The antibodies have a number of improved properties relative to eculizumab, including, e.g., increased serum half-life in a human.
Inventor(s): Andrien, Jr.; Bruce A. (Guilford, CT), Sheridan; Douglas L. (Branford, CT), Tamburini; Paul P. (Kensington, CT), Wang; Yi (Woodbridge, CT)
Assignee: Alexion Pharmaceuticals, Inc. (New Haven, CT)
Application Number:15/492,622
Patent Claims:see list of patent claims

Details for Patent 9,803,007

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Alexion Pharmaceuticals, Inc. ULTOMIRIS ravulizumab-cwvz Injection 761108 12/21/2018 ⤷  Try a Trial 2034-03-07
Alexion Pharmaceuticals, Inc. ULTOMIRIS ravulizumab-cwvz Injection 761108 10/09/2020 ⤷  Try a Trial 2034-03-07
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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