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Last Updated: August 10, 2020

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Patent: 9,365,645

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Summary for Patent: 9,365,645
Title:Methods for controlling the galactosylation profile of recombinantly-expressed proteins
Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g., a hydrolysate-based or a chemically defined medium, with manganese and/or D-galactose.
Inventor(s): Bengea; Cornelia (Auburn, MA), Rives; Lisa M. (Natick, MA), Hossler; Patrick (Westborough, MA)
Assignee: AbbVie, Inc. (North Chicago, IL)
Application Number:15/014,694
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 9,365,645
Patent Claims:see list of patent claims

Details for Patent 9,365,645

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Abbvie Inc HUMIRA adalimumab VIAL 125057 002 2002-12-31   Start Trial AbbVie, Inc. (North Chicago, IL) 2031-04-27 RX search
Abbvie Inc HUMIRA adalimumab SYRINGE 125057 001 2002-12-31   Start Trial AbbVie, Inc. (North Chicago, IL) 2031-04-27 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 9,365,645

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