Multiple-variable dose regimen for treating idiopathic inflammatory bowel disease
Multiple-variable dose methods for treating TNF.alpha.-related disorders, including Crohn\'s disease and psoriasis, comprising administering TNF.alpha. inhibitors, including TNF.alpha. antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.
Hoffman; Rebecca S. (Wilmette, IL), Chartash; Elliot K. (Randolph, NJ), Taylor; Lori K. (Wadsworth, IL), Granneman; George R. (Lindenhurst, IL), Yan; Philip (Vernon Hills, IL)
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