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Generated: August 21, 2019

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Patent: 9,181,233

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Summary for Patent: 9,181,233
Title:Inhibitors of glutaminyl cyclase
Abstract: The invention relates to novel heterocyclic derivatives as inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5). QC catalyzes the intramolecular cyclization of N-terminal glutamine residues into pyroglutamic acid (5-oxo-prolyl, pGlu*) under liberation of ammonia and the intramolecular cyclization of N-terminal glutamate residues into pyroglutamic acid under liberation of water.
Inventor(s): Heiser; Ulrich (Halle/Saale, DE), Ramsbeck; Daniel (Halle/Saale, DE), Hoffmann; Torsten (Halle/Saale, DE), Boehme; Livia (Halle/Saale, DE), Demuth; Hans-Ulrich (Halle/Saale, DE)
Assignee: PROBIODRUG AG (Halle/Saale, DE)
Application Number:13/040,159
Patent Claims:see list of patent claims

Details for Patent 9,181,233

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Biogen Idec TYSABRI natalizumab VIAL; SINGLE-USE 125104 001 2004-11-23   Try a Free Trial PROBIODRUG AG (Halle/Saale, DE) 2030-03-03 RX search
Genzyme LEMTRADA alemtuzumab INJECTABLE;INJECTION 103948 003 2001-05-07   Try a Free Trial PROBIODRUG AG (Halle/Saale, DE) 2030-03-03 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 002 2001-05-07   Try a Free Trial PROBIODRUG AG (Halle/Saale, DE) 2030-03-03 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07   Try a Free Trial PROBIODRUG AG (Halle/Saale, DE) 2030-03-03 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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