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Last Updated: July 3, 2020

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Patent: 8,980,242

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Summary for Patent: 8,980,242
Title:Aliphatic prodrug linker
Abstract: A polymeric prodrug is described which comprises at least one polymer attached via at least one permanent bond to a bicine linker. The bicine linker is attached via a temporary linkage to an amine containing biologically active moiety. The amine containing biologically active moiety--such as a drug--can be released by cleaving the temporary linkage.
Inventor(s): Vetter; Dirk (Heidelberg, DE), Rau; Harald (Heidelberg, DE), Wegge; Thomas (Heidelberg, DE), Hersel; Ulrich (Heidelberg, DE)
Assignee: Ascendis Pharma GmbH (Hellerup, DK)
Application Number:11/993,645
Patent Claims:see list of patent claims

Details for Patent 8,980,242

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Ascendis Pharma GmbH (Hellerup, DK) 2025-06-22 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Ascendis Pharma GmbH (Hellerup, DK) 2025-06-22 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Ascendis Pharma GmbH (Hellerup, DK) 2025-06-22 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Ascendis Pharma GmbH (Hellerup, DK) 2025-06-22 RX Orphan search
Genentech CATHFLO ACTIVASE alteplase VIAL 103172 003 1987-11-13   Start Trial Ascendis Pharma GmbH (Hellerup, DK) 2025-06-22 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 002 1987-11-13   Start Trial Ascendis Pharma GmbH (Hellerup, DK) 2025-06-22 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 001 1987-11-13   Start Trial Ascendis Pharma GmbH (Hellerup, DK) 2025-06-22 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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