You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: July 24, 2024

Patent: 8,663,945

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 8,663,945
Title:Methods of producing anti-TNF-alpha antibodies in mammalian cell culture
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Inventor(s): Pla; Itzcoatl A. (Worcester, MA), Matuck; Joseph C. (Worcester, MA), Fann; John C. (Shrewsbury, MA), Schulz; Christof (Ayer, MA), Roy; Nicole A. (Worcester, MA), Bruton; David F. (Enfield, CT), McIntire; James (Castro Valley, CA), Yu-Hsiang; David Chang (Solana Beach, CA), Seewoester; Thomas (Simi Valley, CA)
Assignee: AbbVie Inc (North Chicago, IL)
Application Number:13/308,075
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 8,663,945
Patent Claims:see list of patent claims

Details for Patent 8,663,945

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Abbvie Inc. HUMIRA adalimumab Injection 125057 December 31, 2002 ⤷  Sign Up 2026-09-13
Abbvie Inc. HUMIRA adalimumab Injection 125057 February 21, 2008 ⤷  Sign Up 2026-09-13
Abbvie Inc. HUMIRA adalimumab Injection 125057 April 24, 2013 ⤷  Sign Up 2026-09-13
Abbvie Inc. HUMIRA adalimumab Injection 125057 September 23, 2014 ⤷  Sign Up 2026-09-13
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.