Patent: 8,168,593

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Summary for Patent: 8,168,593

Title:	Mutated netrin-4, fragments thereof and their use as medicines
Abstract:	A peptide fragment of the netrin-4 protein and nucleic acids coding for the peptide are described. The peptide can inhibit endothelial cell proliferation and cell migration, as well as activate the proliferation and migration of pericytes and smooth muscle cells. Pharmaceutical formulations containing the peptide and/or the nucleic acids can be used to treat a variety of tumoral and non-tumoral pathologies.
Inventor(s):	Plouet; Jean (Paris, FR), Alemany; Monica (Paris, FR)
Assignee:	Centre National de la Recherche Scientifique (Paris, FR) IVS Institut des Vaisseaux et du Sang (Paris, FR)
Application Number:	13/171,756
Patent Claims:	see list of patent claims

Details for Patent 8,168,593

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genentech, Inc.	AVASTIN	bevacizumab	Injection	125085	02/26/2004	⤷ Try a Trial	2024-11-22
Genentech, Inc.	LUCENTIS	ranibizumab	Injection	125156	06/30/2006	⤷ Try a Trial	2024-11-22
Genentech, Inc.	LUCENTIS	ranibizumab	Injection	125156	08/10/2012	⤷ Try a Trial	2024-11-22
Genentech, Inc.	LUCENTIS	ranibizumab	Injection	125156	10/13/2016	⤷ Try a Trial	2024-11-22
Genentech, Inc.	LUCENTIS	ranibizumab	Injection	125156	03/20/2018	⤷ Try a Trial	2024-11-22
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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