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Last Updated: December 7, 2021

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Patent: 8,168,593

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Summary for Patent: 8,168,593
Title:Mutated netrin-4, fragments thereof and their use as medicines
Abstract: A peptide fragment of the netrin-4 protein and nucleic acids coding for the peptide are described. The peptide can inhibit endothelial cell proliferation and cell migration, as well as activate the proliferation and migration of pericytes and smooth muscle cells. Pharmaceutical formulations containing the peptide and/or the nucleic acids can be used to treat a variety of tumoral and non-tumoral pathologies.
Inventor(s): Plouet; Jean (Paris, FR), Alemany; Monica (Paris, FR)
Assignee: Centre National de la Recherche Scientifique (Paris, FR) IVS Institut des Vaisseaux et du Sang (Paris, FR)
Application Number:13/171,756
Patent Claims:see list of patent claims

Details for Patent 8,168,593

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. AVASTIN bevacizumab Injection 125085 2004-02-26 ⤷  Try it Free 2024-11-22
Genentech, Inc. LUCENTIS ranibizumab Injection 125156 2006-06-30 ⤷  Try it Free 2024-11-22
Genentech, Inc. LUCENTIS ranibizumab Injection 125156 2012-08-10 ⤷  Try it Free 2024-11-22
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Express Scripts
Johnson and Johnson

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