Patent: 8,460,895
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Summary for Patent: 8,460,895
| Title: | Method for producing recombinant proteins with a constant content of pCOin the medium |
| Abstract: | A method for the recombinant production of a polypeptide in a eukaryotic host cell modified in the citrate cycle is described, wherein the method comprises cultivating the eukaryotic host cell in a suitable medium under conditions which allow the expression of the polypeptide, wherein the content of dissolved CO(pCO) in the medium is maintained at a constant value in the range of 10% to 20%. |
| Inventor(s): | Eisenkraetzer Detlef, Gaetgens Jochen, Jockwer Alexander, Klinger Christian, Noll Thomas, Bezdek-Sueess Barbara |
| Assignee: | Hoffmann-La Roche Inc. |
| Application Number: | US12920915 |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 8,460,895 |
| Patent Claims: | see list of patent claims |
Details for Patent 8,460,895
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Idec Pharmaceuticals Corp. | RITUXAN | rituximab | Injection | 103737 | February 19, 2002 | 8,460,895 | 2029-03-11 |
| Genentech, Inc. | AVASTIN | bevacizumab | Injection | 125085 | February 26, 2004 | 8,460,895 | 2029-03-11 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
International Patent Family for US Patent 8,460,895
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 2009112250 | ⤷ Start Trial |
| United States of America | 2011159539 | ⤷ Start Trial |
| Japan | 5487124 | ⤷ Start Trial |
| Japan | 2011512852 | ⤷ Start Trial |
| Spain | 2408979 | ⤷ Start Trial |
| European Patent Office | 2283120 | ⤷ Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
