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Last Updated: September 23, 2020

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Patent: 7,560,100

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Summary for Patent: 7,560,100
Title:Mixtures of polypeptides, compositions containing and processes for preparing same, for treating neurodegenerative diseases
Abstract: The invention provides a composition comprising a mixture of polypeptides, wherein each polypeptide (a) is a copolymer of the amino acids L-glutamic acid, L-alanine, L-tyrosine, and L-lysine, and (b) may be in the form of a pharmaceutically acceptable salt; and wherein in the mixture (i) the polypeptides have an average molecular weight in the range 13,500 to 18,500 daltons, (ii) 13% to 38% of the polypeptides have a diethylamide group instead of a carboxyl group present at one end thereof, and (iii) 68% of the polypeptides have a molecular weight between 7,000 and 41,000 daltons. In an embodiment, the average molecular weight is 16,000 daltons. The invention also provides a method of treating a human subject afflicted with a neurodegenerative disease comprising administering to the human subject a therapeutically effective amount of any of the disclosed compositions so as to thereby treat the human subject.
Inventor(s): Pinchasi; Irit (Ra\'anana, IL), Dolitzky; Ben-Zion (Petach-Tikva, IL), Frenkel; Anton (Modiin, IL), Schwartz; Michal (Rehovot, IL), Arnon; Ruth (Rehovot, IL), Aharoni; Rina (Rehovot, IL)
Assignee: Yeda Research and Development Co., Ltd. (Rehovot, IL)
Application Number:11/223,408
Patent Claims:see list of patent claims

Details for Patent 7,560,100

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07   Start Trial Yeda Research and Development Co., Ltd. (Rehovot, IL) 2024-09-09 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 002 2001-05-07   Start Trial Yeda Research and Development Co., Ltd. (Rehovot, IL) 2024-09-09 RX Orphan search
Genzyme LEMTRADA alemtuzumab INJECTABLE;INJECTION 103948 003 2001-05-07   Start Trial Yeda Research and Development Co., Ltd. (Rehovot, IL) 2024-09-09 RX Orphan search
Biogen Idec TYSABRI natalizumab VIAL; SINGLE-USE 125104 001 2004-11-23   Start Trial Yeda Research and Development Co., Ltd. (Rehovot, IL) 2024-09-09 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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