Patent: 7,560,100

Summary for Patent: 7,560,100

Title:	Mixtures of polypeptides, compositions containing and processes for preparing same, for treating neurodegenerative diseases
Abstract:	The invention provides a composition comprising a mixture of polypeptides, wherein each polypeptide (a) is a copolymer of the amino acids L-glutamic acid, L-alanine, L-tyrosine, and L-lysine, and (b) may be in the form of a pharmaceutically acceptable salt; and wherein in the mixture (i) the polypeptides have an average molecular weight in the range 13,500 to 18,500 daltons, (ii) 13% to 38% of the polypeptides have a diethylamide group instead of a carboxyl group present at one end thereof, and (iii) 68% of the polypeptides have a molecular weight between 7,000 and 41,000 daltons. In an embodiment, the average molecular weight is 16,000 daltons. The invention also provides a method of treating a human subject afflicted with a neurodegenerative disease comprising administering to the human subject a therapeutically effective amount of any of the disclosed compositions so as to thereby treat the human subject.
Inventor(s):	Pinchasi; Irit (Ra\'anana, IL), Dolitzky; Ben-Zion (Petach-Tikva, IL), Frenkel; Anton (Modiin, IL), Schwartz; Michal (Rehovot, IL), Arnon; Ruth (Rehovot, IL), Aharoni; Rina (Rehovot, IL)
Assignee:	Yeda Research and Development Co., Ltd. (Rehovot, IL)
Application Number:	11/223,408
Patent Claims:	see list of patent claims

Details for Patent 7,560,100

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genzyme Corporation	CAMPATH	alemtuzumab	Injection	103948	05/07/2001		2024-09-09
Genzyme Corporation	LEMTRADA	alemtuzumab	Injection	103948	11/14/2014		2024-09-09
Genzyme Corporation	CAMPATH	alemtuzumab	Injection	103948	10/12/2004		2024-09-09