Patent: 6,680,168
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Summary for Patent: 6,680,168
Title: | Passive immunization against clostridium difficile disease |
Abstract: | The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile toxin-neutralizing polyclonal immune globulin, C. difficile toxoids, or combinations thereof. Also provided by the invention are C. difficile toxoids, C. difficile toxin-neutralizing polyclonal immune globulin, and methods of identifying subjects that produce C. difficile toxin-neutralizing polyclonal immune globulin. |
Inventor(s): | Thomas, Jr.; William D. (Somerville, MA), Giannasca; Paul J. (Newton, MA), Zhang; Zhenxi (Cambridge, MA), Lei; Wende (Cambridge, MA), Monath; Thomas P. (Harvard, MA) |
Assignee: | Acambis, Inc. (Cambridge, MA) |
Application Number: | 09/815,452 |
Patent Claims: | see list of patent claims |
Details for Patent 6,680,168
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Grifols Therapeutics Llc | BAYGAM, GAMASTAN S/D | immune globulin (human) | Injection | 101134 | 01/11/1944 | ⤷ Try a Trial | 2017-10-20 |
Grifols Therapeutics Llc | GAMMAKED (KENDRION), GAMUNEX-C | immune globulin injection (human) 10% caprylate/chromatography purified | Injection | 125046 | 08/27/2003 | ⤷ Try a Trial | 2017-10-20 |
Octapharma Pharmazeutika Produktionsges.m.b.h. | OCTAGAM | immune globulin intravenous (human) | Injection | 125062 | 05/21/2004 | ⤷ Try a Trial | 2017-10-20 |
Octapharma Pharmazeutika Produktionsges.m.b.h. | OCTAGAM | immune globulin intravenous (human) | Injection | 125062 | 03/26/2007 | ⤷ Try a Trial | 2017-10-20 |
Octapharma Pharmazeutika Produktionsges.m.b.h. | OCTAGAM | immune globulin intravenous (human) | Injection | 125062 | 07/11/2014 | ⤷ Try a Trial | 2017-10-20 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |