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Last Updated: May 30, 2020

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Patent: 6,680,168

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Summary for Patent: 6,680,168
Title: Passive immunization against clostridium difficile disease
Abstract:The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile toxin-neutralizing polyclonal immune globulin, C. difficile toxoids, or combinations thereof. Also provided by the invention are C. difficile toxoids, C. difficile toxin-neutralizing polyclonal immune globulin, and methods of identifying subjects that produce C. difficile toxin-neutralizing polyclonal immune globulin.
Inventor(s): Thomas, Jr.; William D. (Somerville, MA), Giannasca; Paul J. (Newton, MA), Zhang; Zhenxi (Cambridge, MA), Lei; Wende (Cambridge, MA), Monath; Thomas P. (Harvard, MA)
Assignee: Acambis, Inc. (Cambridge, MA)
Application Number:09/815,452
Patent Claims:see list of patent claims

Details for Patent 6,680,168

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Octapharma Usa Inc OCTAGAM IMMUNE GLOBULIN (HUMAN) immune globulin SOLUTION 125062 1 2004-05-21   Start Trial Acambis, Inc. (Cambridge, MA) 2017-10-20 search
Grifols Usa, Llc GAMUNEX-C immune globulin (human) INJECTION 125046 1 2010-10-13   Start Trial Acambis, Inc. (Cambridge, MA) 2017-10-20 search
Grifols Usa, Llc GAMASTAN immune globulin (human) INJECTION, SOLUTION 101134 1 1996-08-14   Start Trial Acambis, Inc. (Cambridge, MA) 2017-10-20 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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