Last Updated: October 1, 2026

Patent: 6,331,415

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Summary for Patent: 6,331,415

Title:	Methods of producing immunoglobulins, vectors and transformed host cells for use therein
Abstract:	The invention relates to processes for producing an immunoglobulin or an immunologically functional immunoglobulin fragment containing at least the variable domains of the immunoglobulin heavy and light chains. The processes can use one or more vectors which produce both the heavy and light chains or fragments thereof in a single cell. The invention also relates to the vectors used to produce the immunoglobulin or fragment, and to cells transformed with the vectors.
Inventor(s):	Shmuel Cabilly, Herbert L. Heyneker, William E. Holmes, Arthur D. Riggs, Ronald B. Wetzel
Assignee:	Genentech Inc
Application Number:	US07/205,419
Patent Claims:	see list of patent claims

Details for Patent 6,331,415

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Imclone Llc A Wholly-owned Subsidiary Of Eli Lilly And Company	ERBITUX	cetuximab	Injection	125084	12-Feb-04	⤷ Start Trial	2018-12-18
Imclone Llc A Wholly-owned Subsidiary Of Eli Lilly And Company	ERBITUX	cetuximab	Injection	125084	28-Mar-07	⤷ Start Trial	2018-12-18
Novartis Pharmaceuticals Corporation	ARZERRA	ofatumumab	Injection	125326	26-Oct-09	⤷ Start Trial	2018-12-18
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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