A plastic adaptor top for adapting to a chosen syringe a standard cartridge of the kind having a neck with a flange and being closed by a rubber membrane sealingly secured against the flange by a metal cover having its edge beaded behind the flange. This plastic top has a bore for receiving the neck part of the cartridge, which bore has a diameter making it fit over the metal cover and is provided with protrusions gripping behind the edge of the metal cover when the neck part is inserted in the bore. The outer contour of the adaptor top is provided with threads coaxial with the bore to receive a needle hub in a way causing the needle to penetrate the membrane of the cartridge when the hub is mounted on the thread of the plastic top.
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