Patent: 5,929,028
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Summary for Patent: 5,929,028
Title: | Liquid gonadotropin containing formulations |
Abstract: | The invention concerns a liquid gonadotropin-containing formulation characterised in that the formulation comprises a gonadotropin and stabilising amounts of a polycarboxylic acid or a salt thereof and of a thioether compound. The particular proteins (e.g. LH, TSH, FSH, or HCG) are in admixture with the particular stabilizers in an aqueous solution. The preparations contain a sufficient amount of the polycarboxylic acid or a salt thereof, preferably sodium citrate, and a sufficient amount of the thioether compound, preferably methionine, to stabilize the protein. The preparations preferably also include a nonreducing disaccharide like sucrose, and a non-ionic surfactant. |
Inventor(s): | Skrabanja; Arnold Titus Philip (An Nijmegen, NL), van den Oetelaar; Petrus Johannes Maria (Et Heesch, NL) |
Assignee: | Akzo Nobel, N.V. (Arnhem, NL) |
Application Number: | 09/006,812 |
Patent Claims: | see list of patent claims |
Details for Patent 5,929,028
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Ferring Pharmaceuticals Inc. | NOVAREL | chorionic gonadotropin | For Injection | 017016 | 01/15/1974 | ⤷ Try a Trial | 2017-01-15 |
Ferring Pharmaceuticals Inc. | NOVAREL | chorionic gonadotropin | For Injection | 017016 | 12/27/1984 | ⤷ Try a Trial | 2017-01-15 |
Ferring Pharmaceuticals Inc. | NOVAREL | chorionic gonadotropin | For Injection | 017016 | 02/15/1985 | ⤷ Try a Trial | 2017-01-15 |
Ferring Pharmaceuticals Inc. | NOVAREL | chorionic gonadotropin | For Injection | 017016 | 02/16/1990 | ⤷ Try a Trial | 2017-01-15 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
International Patent Family for US Patent 5,929,028
Country | Patent Number | Estimated Expiration |
---|---|---|
South Africa | 9883 | ⤷ Try a Trial |
Taiwan | 518235 | ⤷ Try a Trial |
Turkey | 199800062 | ⤷ Try a Trial |
Saudi Arabia | 98181124 | ⤷ Try a Trial |
>Country | >Patent Number | >Estimated Expiration |