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Last Updated: September 22, 2020

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Patent: 5,695,968

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Summary for Patent: 5,695,968
Title: Process for production of D-.alpha.-amino acids
Abstract:The present invention is directed to a gene which is related to a D-N-carbamoyl-.alpha.-amino acid amidohydrolase which is an enzyme capable of converting D-N-carbamoyl-.alpha.-amino acids into D-.alpha.-amino acids; a recombinant plasmid in which a DNA fragment containing the gene is incorporated into a vector; a microorganism belonging to the genus Escherichia, Pseudomonas, Flavobacterium, Bacillus, Serratia, Corynebacterium, or Brevibacterium, which is transformed by incorporating the recombinant plasmid thereinto; a process for the production of D-N-carbamoyl-.alpha.-amino acid amidohydrolases, comprising the steps of cultivating the transformed microorganism and collecting the desired product therefrom; a D-N-carbamoyl-.alpha.-amino acid amidohydrolase obtained by the method; and a process for the production of D-.alpha.-amino acids with the aid of an action of the enzyme. The D-N-carbamoyl-.alpha.-amino acid amidohydrolase can be fixed on a support for immobilization and used as an immobilized enzyme.
Inventor(s): Nanba; Hirokazu (Takasago, JP), Yamada; Yukio (Kakogawa, JP), Takano; Masayuki (Akashi, JP), Ikenaka; Yasuhiro (Akashi, JP), Takahashi; Satomi (Kobe, JP), Yajima; Kazuyoshi (Kobe, JP)
Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha (Osaka, JP)
Application Number:08/479,638
Patent Claims:see list of patent claims

Details for Patent 5,695,968

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Baxalta Us Inc. RECOMBINATE antihemophilic factor recombinant KIT 103375 1 2010-03-15   Start Trial Kanegafuchi Kagaku Kogyo Kabushiki Kaisha (Osaka, JP) 2014-12-09 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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