Last Updated: November 4, 2026

Patent: 5,460,812

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Summary for Patent: 5,460,812

Title:	Compositions of digestive enzymes and salts of bile acids and process for preparation thereof
Abstract:	Disclosed are gastric acid-resistant polymer-coated buffered digestive enzymes/ursodeoxycholate compositions, process for their preparations and methods of treating digestive disorders, pancreatic enzyme insufficiency, impaired liver function, cystic fibrosis, for regulating the absorption of dietary iron and cholesterol, and for dissolving gallstones by administering the compositions to a mammal in need of such treatment.
Inventor(s):	Sipos; Tibor (Lebanon, NJ)
Assignee:	Digestive Care Inc. (Lebanon, NJ)
Application Number:	08/129,250
Patent Claims:	see list of patent claims

Details for Patent 5,460,812

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Discure Medical, Llc	CHYMODIACTIN	chymopapain	For Injection	018663	November 10, 1982	5,460,812	2013-09-29
Discure Medical, Llc	CHYMODIACTIN	chymopapain	For Injection	018663	August 21, 1984	5,460,812	2013-09-29
Organon Usa Inc., A Subsidiary Of Merck & Co., Inc.	COTAZYM	pancrelipase	Capsule, Delayed Release	020580	December 9, 1996	5,460,812	2013-09-29
Abbvie Inc.	CREON	pancrelipase	Capsule, Delayed Release	020725	April 30, 2009	5,460,812	2013-09-29
Abbvie Inc.	CREON	pancrelipase	Capsule, Delayed Release	020725	June 10, 2011	5,460,812	2013-09-29
Abbvie Inc.	CREON	pancrelipase	Capsule, Delayed Release	020725	March 14, 2013	5,460,812	2013-09-29
Digestive Care, Inc.	PERTZYE	pancrelipase	Capsule, Delayed Release	022175	May 17, 2012	5,460,812	2013-09-29
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 5,460,812

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Country	Patent Number	Estimated Expiration
Australia	4133193	⤷ Start Trial
Australia	666015	⤷ Start Trial
Canada	2096002	⤷ Start Trial
European Patent Office	0576938	⤷ Start Trial
United States of America	5260074	⤷ Start Trial
United States of America	5324514	⤷ Start Trial
United States of America	5578304	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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