Last Updated: November 8, 2026

Patent: 11,332,529

Summary for Patent: 11,332,529

Title:	Methods of treating colorectal cancer
Abstract:	This disclosure provides methods for treating a tumor derived from a colorectal cancer exhibiting a high degree of microsatellite instability in a subject comprising administering to the subject an anti-PD-1 antibody. In some embodiments, the method further comprises administering an anti-CTLA-4 antibody. In some embodiments, the colorectal cancer is rectal cancer, colon cancer, or any combination thereof.
Inventor(s):	Michael AXELSON
Assignee:	Bristol Myers Squibb Co
Application Number:	US16/306,290
Patent Claims:	see list of patent claims

Details for Patent 11,332,529

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bristol-myers Squibb Company	OPDIVO	nivolumab	Injection	125554	December 22, 2014	⤷ Start Trial	2037-06-02
Bristol-myers Squibb Company	OPDIVO	nivolumab	Injection	125554	October 4, 2017	⤷ Start Trial	2037-06-02
Bristol-myers Squibb Company	OPDIVO	nivolumab	Injection	125554	August 27, 2021	⤷ Start Trial	2037-06-02
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,332,529

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Country	Patent Number	Estimated Expiration
China	109476754	⤷ Start Trial
European Patent Office	3464373	⤷ Start Trial
European Patent Office	3988570	⤷ Start Trial
Spain	2897964	⤷ Start Trial
Japan	2019517512	⤷ Start Trial
Japan	2023002567	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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