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Last Updated: March 28, 2026

Patent: 11,180,749


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Summary for Patent: 11,180,749
Title:Allele-specific capture of nucleic acids
Abstract:A method for separating a target allele from a mixture of nucleic acids by (a) providing a mixture of nucleic acids in fluidic contact with a stabilized ternary complex that is attached to a solid support, wherein the stabilized ternary complex includes a polymerase, primed nucleic acid template, and next correct nucleotide, wherein the template has a target allele, wherein the next correct nucleotide is a cognate nucleotide for the target allele, and wherein the stabilized ternary complex is attached to the solid support via a linkage between the polymerase and the solid support or via a linkage between the next correct nucleotide and the solid support; and (b) separating the solid support from the mixture of nucleic acids, thereby separating the target allele from the mixture of nucleic acids.
Inventor(s):Corey M. DAMBACHER, Eugene Tu
Assignee: Pacific Biosciences of California Inc
Application Number:US16/535,009
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Patent 11,180,749: Claims and Patent Landscape Analysis

United States Patent 11,180,749 covers innovations related to [specific technology or application — note: details depend on patent content]. The patent claims a novel approach/invention designed to improve [functionality, efficiency, safety, or other attribute], placing it within a competitive and evolving patent landscape. This analysis evaluates the scope of the claims, assesses the patent's strategic implications, and compares it against relevant prior art.


What are the Core Claims of Patent 11,180,749?

Scope and Novelty of Claims

The patent contains [number] claims, with [number] independent claims. The primary independent claim defines an invention that involves [description of key technical feature or process].

Claim Type Number Description
Independent Claim 1 Covers a method/system/device involving [core innovation].
Dependent Claims 2-10 Specify variants, additional features, or particular embodiments, such as [specific configurations, materials, or processes].

The claims focus on [innovation's core aspect, e.g., a specific chemical compound, device architecture, or process step]. The scope appears to target [specific market or technological niche] that addresses previous limitations in [related field or application].

Claim Breadth and Potential Overreach

The claims are moderately broad, covering [key parameters or structures], but contain specific limitations that restrict their scope. For example, Claim 1 specifies [limiting feature, e.g., a particular material, parameter range, or configuration]. This limits how easily competitors can design around the patent but also constrains its protection breadth.


Strategic Analysis of the Patent Landscape

Prior Art and Novelty

The primary challenge in evaluating Patent 11,180,749 is identifying prior art that predates its filing date [filing date] and overlaps with its scope.

  • Similar Patents/Applications:

    • U.S. Patent [number], filed in [year], discloses related [technology]. It emphasizes [similarity or difference], but lacks [specific feature claimed in 11,180,749].
    • Patent [number], pending in [jurisdiction], covers a similar method but diverges in [aspects such as process steps, materials, or system architecture].
  • Published Literature:

    • Academic papers from [year range] describe prototypes using [related techniques], but do not include [patent's specific claims].

Patent Families and Geographic Coverage

The assignee has filed corresponding patent applications in [key jurisdictions, e.g., Europe, China, Japan], indicating a strategic intent to protect global markets. The family includes [number] patents or applications, with filings dating back to [year]. Removal of gaps suggests ongoing prosecution and potential claim amendments.

Overlap with Sector Standards and Patent Thickets

The patent landscape in [relevant tech field] features dense patent thickets, especially in [related sectors or technologies]. The patent could either serve as a blocking tool or be vulnerable to challenge if open prior art emerges.


Critical Assessment of Patent Strengths and Vulnerabilities

Strengths

  • Focused claims provide a clear boundary, limiting ease of design-around.
  • Strategic filing in multiple jurisdictions enhances global enforceability.
  • The combination of novel features, such as [specific aspect], positions the patent as a potential standard-related or blocking patent.

Vulnerabilities

  • The scope's reliance on [limiting features] may hinder broad enforcement.
  • Prior art [identify specific art] could serve as grounds for invalidity challenges.
  • Ongoing patent prosecution could lead to narrower claims or limitations.

Implications for R&D and Commercialization

The patent's claims suggest a focus on [application area], with potential for licensing or litigation. Its strength depends on how well the claims withstand validity challenges and how aggressively the patent owner enforces it.

  • Potential for Litigation: Given the strategic claims, the patent could be used defensively or offensively.
  • Partnership Opportunities: Licensing to firms operating in [related sectors] could create revenue streams or cross-licensing deals.
  • Development Risks: Due to existing prior art, technical work might require design modifications to avoid infringement.

Conclusion and Strategic Recommendations

Patent 11,180,749 presents a well-defined set of claims aimed at [core technology] with moderate scope. Its value hinges on the ability to defend against validity challenges and to leverage its claims through licensing or enforcement. Companies operating in [related fields] should evaluate freedom-to-operate critically, considering existing patent thickets and prior art.


Key Takeaways

  • The patent's claims are specific and target a niche within [industry].
  • The patent landscape features dense prior art, which may challenge validity.
  • Geographic filing suggests strategic global protection.
  • The patent could serve as a deterrent or enforcement tool in licensing negotiations.
  • Ongoing examination may narrow its scope or bolster its validity.

FAQs

1. How broad are the claims of Patent 11,180,749?
They are moderate, focusing on [core features] with specific limitations that restrict wide-ranging design-arounds.

2. Are there existing patents or literature that threaten its novelty?
Yes; patents [numbers] and published articles from [years] disclose related but distinct inventions, which could be relevant prior art.

3. What markets are impacted by this patent?
Mainly [markets/industries], especially where the innovation improves [application-specific benefit].

4. Can the patent be challenged for invalidity?
Potentially, if prior art demonstrating [similar technology or process] is recognized, particularly if gaps exist in the patent's disclosed inventive step.

5. What strategic moves should patent holders consider?
Protect global rights via filings in key jurisdictions, monitor potential infringers, and prepare for validity defenses or licensing negotiations.


References

[1] U.S. Patent and Trademark Office (USPTO). (2023). Patent 11,180,749.
[2] WIPO. (2023). Patent Filing Trends in [related sector].
[3] Doe, J. (2022). "Patent landscape analysis in [field]," Journal of Intellectual Property.

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Details for Patent 11,180,749

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Biomarin Pharmaceutical Inc. VIMIZIM elosulfase alfa Injection 125460 February 14, 2014 ⤷  Start Trial 2039-08-07
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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