Last Updated: July 4, 2026

Patent: 10,851,118

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Summary for Patent: 10,851,118

Title:	Compositions and methods for inhibiting arginase activity
Abstract:	The invention relates to a novel class of compounds that exhibit activity inhibitory activity toward arginase, and pharmaceutical compositions comprising the compounds of the invention. Also provided herein are methods of treating cancer with the arginase inhibitors of the invention.
Inventor(s):	Sjogren Eric B., Li Jim, Van Zandt Michael, Whitehouse Darren
Assignee:	CALITHERA BIOSCIENCES, INC.
Application Number:	US16101275
Patent Claims:	see list of patent claims

Details for Patent 10,851,118

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Recordati Rare Diseases, Inc.	ELSPAR	asparaginase	For Injection	101063	January 10, 1978	⤷ Start Trial	2038-08-10
Amgen Inc.	NEUPOGEN	filgrastim	Injection	103353	February 20, 1991	⤷ Start Trial	2038-08-10
Amgen Inc.	NEUPOGEN	filgrastim	Injection	103353	June 28, 2000	⤷ Start Trial	2038-08-10
Genzyme Corporation	CAMPATH	alemtuzumab	Injection	103948	May 07, 2001	⤷ Start Trial	2038-08-10
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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