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Last Updated: December 16, 2025

Patent: 10,744,204


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Summary for Patent: 10,744,204
Title:Conjugated compounds comprising cysteine-engineered antibodies
Abstract:This disclosure provides conjugate compounds comprising antibodies and fragments thereof engineered with one or more reactive cysteine residues and more specifically to conjugate compounds with therapeutic or diagnostic applications. The conjugate compounds comprise cysteine-engineered antibodies or fragments thereof conjugated, for example, with chemotherapeutic drugs, toxins, and detection labels such as radionuclides or fluorophores. The disclosure also provides methods of using the disclosed conjugate compounds for in vitro, in situ, ex vivo, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.
Inventor(s):Changshou Gao, Godfrey RAINEY, Cuihua GAO
Assignee: MedImmune LLC
Application Number:US15/302,036
Patent Claims:see list of patent claims

Details for Patent 10,744,204

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Sanofi-aventis U.s. Llc ADLYXIN lixisenatide Injection 208471 July 27, 2016 10,744,204 2035-04-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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