Last Updated: June 25, 2026

Patent: 10,723,775


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Summary for Patent: 10,723,775
Title:Method for purifying darbepoetin alfa
Abstract: The present invention relates to a method for purifying darbepoetin alfa by selectively separating only a structural isoform having a high content of sialic acid from a mixture of structural isoforms of darbepoetin alfa having various contents of sialic acid. Since the method of the present invention is a novel method for purifying darbepoetin alfa which can be conveniently and simply produced, it is possible to remarkably increase productivity due to process efficiency improvement, as well as to yield high purity darbepoetin alfa when mass-producing darbepoetin alfa according to the present invention.
Inventor(s): Lee; Yoon Jung (Yongin-si, KR), Kim; Kyung Hwa (Busan, KR), Yang; Yoo Hee (Yongin-si, KR), Yoo; Jung Min (Seoul, KR), Kim; Se Jun (Gwacheon-si, KR), Moon; Ji Hyun (Seoul, KR), Oh; Hoo Keun (Suwon-si, KR), Lee; Dong Eok (Seoul, KR), Lee; Won Jeong (Seoul, KR), Lee; Jung Rok (Busan, KR), Lee; Chung Min (Yongin-si, KR), Choi; Eun Young (Seoul, KR), Ha; Gyong Sik (Suwon-si, KR)
Assignee: CJ Healthcare Corporation (Seoul, KR)
Application Number:15/039,569
Patent Claims:see list of patent claims

Details for Patent 10,723,775

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Amgen Inc. ARANESP darbepoetin alpha Injection 103951 September 17, 2001 ⤷  Start Trial 2034-11-28
Amgen Inc. ARANESP darbepoetin alpha Injection 103951 July 19, 2002 ⤷  Start Trial 2034-11-28
Amgen Inc. ARANESP darbepoetin alpha Injection 103951 December 17, 2002 ⤷  Start Trial 2034-11-28
Amgen Inc. ARANESP darbepoetin alpha Injection 103951 December 12, 2003 ⤷  Start Trial 2034-11-28
Amgen Inc. ARANESP darbepoetin alpha Injection 103951 June 29, 2006 ⤷  Start Trial 2034-11-28
Amgen Inc. ARANESP darbepoetin alpha Injection 103951 ⤷  Start Trial 2034-11-28
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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