Patent: 10,723,775
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Summary for Patent: 10,723,775
| Title: | Method for purifying darbepoetin alfa |
| Abstract: | The present invention relates to a method for purifying darbepoetin alfa by selectively separating only a structural isoform having a high content of sialic acid from a mixture of structural isoforms of darbepoetin alfa having various contents of sialic acid. Since the method of the present invention is a novel method for purifying darbepoetin alfa which can be conveniently and simply produced, it is possible to remarkably increase productivity due to process efficiency improvement, as well as to yield high purity darbepoetin alfa when mass-producing darbepoetin alfa according to the present invention. |
| Inventor(s): | Lee; Yoon Jung (Yongin-si, KR), Kim; Kyung Hwa (Busan, KR), Yang; Yoo Hee (Yongin-si, KR), Yoo; Jung Min (Seoul, KR), Kim; Se Jun (Gwacheon-si, KR), Moon; Ji Hyun (Seoul, KR), Oh; Hoo Keun (Suwon-si, KR), Lee; Dong Eok (Seoul, KR), Lee; Won Jeong (Seoul, KR), Lee; Jung Rok (Busan, KR), Lee; Chung Min (Yongin-si, KR), Choi; Eun Young (Seoul, KR), Ha; Gyong Sik (Suwon-si, KR) |
| Assignee: | CJ Healthcare Corporation (Seoul, KR) |
| Application Number: | 15/039,569 |
| Patent Claims: | see list of patent claims |
Details for Patent 10,723,775
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Amgen Inc. | ARANESP | darbepoetin alpha | Injection | 103951 | September 17, 2001 | ⤷ Start Trial | 2034-11-28 |
| Amgen Inc. | ARANESP | darbepoetin alpha | Injection | 103951 | July 19, 2002 | ⤷ Start Trial | 2034-11-28 |
| Amgen Inc. | ARANESP | darbepoetin alpha | Injection | 103951 | December 17, 2002 | ⤷ Start Trial | 2034-11-28 |
| Amgen Inc. | ARANESP | darbepoetin alpha | Injection | 103951 | December 12, 2003 | ⤷ Start Trial | 2034-11-28 |
| Amgen Inc. | ARANESP | darbepoetin alpha | Injection | 103951 | June 29, 2006 | ⤷ Start Trial | 2034-11-28 |
| Amgen Inc. | ARANESP | darbepoetin alpha | Injection | 103951 | ⤷ Start Trial | 2034-11-28 | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
International Patent Family for US Patent 10,723,775
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| Brazil | 112016009421 | ⤷ Start Trial |
| China | 105764915 | ⤷ Start Trial |
| European Patent Office | 3075740 | ⤷ Start Trial |
| Hong Kong | 1223633 | ⤷ Start Trial |
| Japan | 2016538261 | ⤷ Start Trial |
| Japan | 6232130 | ⤷ Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
