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Last Updated: March 29, 2024

Patent: 10,675,328


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Summary for Patent: 10,675,328
Title:Compositions and methods for treatment of Gcase related disease states
Abstract: Disclosed are compositions and methods of treating a neurodegenerative disease in an individual. The methods disclose administration of an Integrin .alpha.4.beta.1, Very Late Antigen-4 positive neural precursor cell (\"VLA4+ NPC\") transfected with a lentivirus overexpressing wild type GCase to an individual having a neurodegenerative disorder. The neurodegenerative disease may include lipid storage diseases, for example Gaucher disease, Parkinson\'s disease (PD), Dementia with Lewy bodies.
Inventor(s): Sun; Ying (Mason, OH)
Assignee: Children\'s Hospital Medical Center (Cincinnati, OH)
Application Number:15/896,423
Patent Claims:see list of patent claims

Details for Patent 10,675,328

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genzyme Corporation CEREZYME imiglucerase For Injection 020367 05/23/1994 ⤷  Try a Trial 2037-02-14
Genzyme Corporation CEREZYME imiglucerase For Injection 020367 09/22/1999 ⤷  Try a Trial 2037-02-14
Takeda Pharmaceuticals U.s.a., Inc. VPRIV velaglucerase alfa For Injection 022575 02/26/2010 ⤷  Try a Trial 2037-02-14
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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