You are 3 steps away
from making better decisions

Serving leading biopharmaceutical companies globally:

Medtronic
Merck
McKinsey
Boehringer Ingelheim
Dow
Colorcon

Last Updated: May 13, 2021

DrugPatentWatch Database Preview

Patent: 10,544,125

➤ Get the DrugPatentWatch Daily Briefing
» See Plans and Pricing

« Back to Dashboard

Summary for Patent: 10,544,125
Title:Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)meth- yl)cyclopropanamine, its crystalline form and its salts
Abstract: The present invention relates a new process to synthesize 1-((4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)meth- yl)cyclopropanamine (AL3818). A stable crystalline form of Al3818 has been prepared. Salts and their crystalline forms of AL3818 have been also prepared. Anti-cancer and optometric activities of AL3818 and its salts have been further tested. New process has been outlined in Scheme I. ##STR00001##
Inventor(s): Chen; Guoqing Paul (Westlake, CA), Yan; Changren (Camarillo, CA)
Assignee: Advenchen Pharmaceuticals, LLC (Moorpark, CA)
Application Number:16/125,401
Patent Claims:see list of patent claims

Details for Patent 10,544,125

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Janssen Biotech DARZALEX daratumumab INJECTABLE;INJECTION 761036 002 2015-11-16   Get Started for $10 Advenchen Pharmaceuticals, LLC (Moorpark, CA) 2035-05-04 RX Orphan search
Janssen Biotech DARZALEX daratumumab INJECTABLE;INJECTION 761036 001 2015-11-16   Get Started for $10 Advenchen Pharmaceuticals, LLC (Moorpark, CA) 2035-05-04 RX Orphan search
Bristol Myers Squibb EMPLICITI elotuzumab INJECTABLE;INJECTION 761035 002 2015-11-30   Get Started for $10 Advenchen Pharmaceuticals, LLC (Moorpark, CA) 2035-05-04 RX Orphan search
Bristol Myers Squibb EMPLICITI elotuzumab INJECTABLE;INJECTION 761035 001 2015-11-30   Get Started for $10 Advenchen Pharmaceuticals, LLC (Moorpark, CA) 2035-05-04 RX Orphan search
Amgen BLINCYTO blinatumomab INJECTABLE;INJECTION 125557 001 2014-12-03   Get Started for $10 Advenchen Pharmaceuticals, LLC (Moorpark, CA) 2035-05-04 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Dow
Moodys
Express Scripts
Baxter
Medtronic
Colorcon

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.