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Last Updated: September 27, 2020

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Patent: 10,493,080

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Summary for Patent: 10,493,080
Title:Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
Abstract: The present invention provides methods of inducing differentiation of oligodendrocyte progenitor cells to a mature myelinating cell fate with a neurotransmitter receptor modulating agent. The present invention also provides methods of stimulating increased myelination in a subject in need thereof by administering said neurotransmitter receptor modulating agent. Methods of treating a subject having a demyelinating disease using a neurotransmitter receptor modulating agent are also provided.
Inventor(s): Schultz; Peter (La Jolla, CA), Lairson; Luke (San Diego, CA), Deshmukh; Vishal (La Jolla, CA), Lyssiotis; Costas (Boston, MA)
Assignee: The Scripps Research Institute (La Jolla, CA) Novartis AG (Basel, CH)
Application Number:15/418,572
Patent Claims:see list of patent claims

Details for Patent 10,493,080

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bayer Healthcare Pharms BETASERON interferon beta-1b VIAL; SUBCUTANEOUS 103471 001 1993-07-23   Start Trial The Scripps Research Institute (La Jolla, CA) Novartis AG (Basel, CH) 2031-02-18 RX Orphan search
Biogen AVONEX interferon beta-1a VIAL 103628 001 1996-05-17   Start Trial The Scripps Research Institute (La Jolla, CA) Novartis AG (Basel, CH) 2031-02-18 RX search
Serono Inc REBIF interferon beta-1a SYRINGE 103780 001 2002-03-07   Start Trial The Scripps Research Institute (La Jolla, CA) Novartis AG (Basel, CH) 2031-02-18 RX search
Serono Inc REBIF interferon beta-1a SYRINGE 103780 002 2002-03-07   Start Trial The Scripps Research Institute (La Jolla, CA) Novartis AG (Basel, CH) 2031-02-18 RX search
Jubilant Hollisterstier Llc POSITIVE SKIN TEST CONTROL - HISTAMINE histamine INJECTION 103891 1 1995-06-15   Start Trial The Scripps Research Institute (La Jolla, CA) Novartis AG (Basel, CH) 2031-02-18 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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