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Last Updated: December 2, 2021

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Patent: 10,493,080

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Summary for Patent: 10,493,080
Title:Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
Abstract: The present invention provides methods of inducing differentiation of oligodendrocyte progenitor cells to a mature myelinating cell fate with a neurotransmitter receptor modulating agent. The present invention also provides methods of stimulating increased myelination in a subject in need thereof by administering said neurotransmitter receptor modulating agent. Methods of treating a subject having a demyelinating disease using a neurotransmitter receptor modulating agent are also provided.
Inventor(s): Schultz; Peter (La Jolla, CA), Lairson; Luke (San Diego, CA), Deshmukh; Vishal (La Jolla, CA), Lyssiotis; Costas (Boston, MA)
Assignee: The Scripps Research Institute (La Jolla, CA) Novartis AG (Basel, CH)
Application Number:15/418,572
Patent Claims:see list of patent claims

Details for Patent 10,493,080

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bayer Healthcare Pharmaceuticals Inc. BETASERON interferon beta-1b For Injection 103471 1993-07-23 ⤷  Free Forever Trial 2031-02-18
Biogen Inc. AVONEX interferon beta-1a For Injection 103628 1996-05-17 ⤷  Free Forever Trial 2031-02-18
Biogen Inc. AVONEX interferon beta-1a Injection 103628 2003-05-28 ⤷  Free Forever Trial 2031-02-18
Biogen Inc. AVONEX interferon beta-1a Injection 103628 2012-02-27 ⤷  Free Forever Trial 2031-02-18
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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