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Last Updated: November 28, 2021

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Patent: 10,434,172

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Summary for Patent: 10,434,172
Title:Methods of treating generalized pustular psoriasis (GPP) using IL-17 antagonists
Abstract: The disclosure is directed to methods, treatment regimens, uses, kits and therapies for treating Generalized Pustular Psoriasis (GPP). These methods, treatment regimens, uses, kits and therapies utilize, inter alia, administration of an IL-17 antagonist, e.g., an IL-17 antibody, such as secukinumab. Additionally disclosed are improved methods for treating plaque-type psoriasis that utilize up-titration and down-titration of the IL-17 antagonist, e.g., an IL-17 antibody, such as secukinumab, as well as modification of dose frequency. Further disclosed are methods of treating palmoplantar pustular psoriasis using the disclosed IL-17 antagonists, e.g., IL-17 antibodies, such as secukinumab.
Inventor(s): Papavassilis; Charis (Lorrach, DE), Sander; Oliver (Basel, CH), Shima; Tomohiro (Tokyo, JP), Kitamura; Susumu (Yokohama, JP)
Assignee: Novartis AG (Basel, CH)
Application Number:14/911,387
Patent Claims:see list of patent claims

Details for Patent 10,434,172

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Janssen Biotech, Inc. STELARA ustekinumab Injection 125261 2009-09-25 ⤷  Free Forever Trial 2033-08-15
Janssen Biotech, Inc. STELARA ustekinumab Injection 125261 2009-12-30 ⤷  Free Forever Trial 2033-08-15
Novartis Pharmaceuticals Corporation COSENTYX secukinumab Injection 125504 2015-01-21 ⤷  Free Forever Trial 2033-08-15
Novartis Pharmaceuticals Corporation COSENTYX secukinumab For Injection 125504 2015-01-21 ⤷  Free Forever Trial 2033-08-15
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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