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Last Updated: May 1, 2024

Patent: 10,370,449

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Summary for Patent: 10,370,449

Title:	Methods for treating skin infection by administering an IL-4R antagonist
Abstract:	The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.
Inventor(s):	Graham; Neil (Croton-on-Hudson, NY), Ardeleanu; Marius (White Plains, NY), Radin; Allen (New York, NY), Hamilton; Jennifer D. (Hopewell Junction, NY), Teper; Ariel (Hastings-on-Hudson, NY)
Assignee:	Regeneron Pharmaceuticals, Inc. (Tarrytown, NY) Sanofi Biotechnology (Paris, FR)
Application Number:	14/632,988
Patent Claims:	see list of patent claims

Details for Patent 10,370,449

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Regeneron Pharmaceuticals, Inc.	DUPIXENT	dupilumab	Injection	761055	03/28/2017	⤷ Try a Trial	2034-09-24
Regeneron Pharmaceuticals, Inc.	DUPIXENT	dupilumab	Injection	761055	10/19/2018	⤷ Try a Trial	2034-09-24
Regeneron Pharmaceuticals, Inc.	DUPIXENT	dupilumab	Injection	761055	06/18/2020	⤷ Try a Trial	2034-09-24
Regeneron Pharmaceuticals, Inc.	DUPIXENT	dupilumab	Injection	761055	06/14/2021	⤷ Try a Trial	2034-09-24
Regeneron Pharmaceuticals, Inc.	DUPIXENT	dupilumab	Injection	761055	10/20/2021	⤷ Try a Trial	2034-09-24
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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