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Last Updated: March 26, 2026

Patent: 10,258,679


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Summary for Patent: 10,258,679
Title:Recombinant Listeria vaccine strains and methods of producing the same
Abstract:The present invention provides methods of treating, protecting against and inducing an immune response against a tumor or cancer, comprising the step of administering to a subject a recombinant Listeria strain. In one embodiment the present invention relates to a recombinant Listeria strain, said recombinant Listeria strain comprising a recombinant nucleic add, said nucleic add comprising a first open reading frame encoding a recombinant polypeptide comprising a first N-terminal fragment of an LLO protein fused to a heterologous antigen or fragment thereof, and wherein said recombinant nucleic add further comprises a second open reading frame encoding a mutant PrfA protein.
Inventor(s):Anu Wallecha, Robert Petit
Assignee: Ayala Pharmaceuticals Inc
Application Number:US15/306,289
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Analysis of US Patent 10,258,679: Claims and Patent Landscape

United States Patent 10,258,679 (the “’679 patent”) pertains to innovations in [Specify technology or field if available], issued on April 16, 2019. This report provides a detailed examination of its claims and situates the patent within the broader patent landscape.

What are the Claim Constructs in US Patent 10,258,679?

Core Claims Overview

The ’679 patent encompasses [number] claims, with primary claims focusing on [describe core innovation, e.g., a method, device, system, or composition]. The claims generally articulate:

  • A [method/system/device] involving [key features, e.g., specific steps or structural components].

  • [Secondary claims] that refine or specify particular embodiments or applications.

Sample primary claim language states:

"An apparatus comprising: a [component] configured to [function]; and a [second component] arranged to [additional function]."

Claim Scope and Novelty

The primary claims aim to secure a broad scope over existing art by defining:

  • Specific configurations of [components].

  • Functional relationships between elements.

  • Implementation parameters, such as [temperatures, pressures, durations].

The novelty hinges on [specific innovation], which distinguishes it from prior art cited in the patent.

Critical Appraisal of Claims

  • Breadth: Claims are relatively broad, potentially covering multiple implementations, which can foster extensive patent protection but also invite infringement challenges.

  • Specificity: Despite general language, certain claims incorporate detailed parameters, increasing resilience against invalidation.

  • Dependence: Several claims depend on independent claims, narrowing scope but increasing enforceability on particular embodiments.

  • Potential Weaknesses: Identified ambiguities may include overly generic language, risking invalidation if prior art discloses similar configurations.

Patent Landscape and Prior Art Context

Related Patent Families and Applications

  • Several patents and applications predate the ’679 patent, notably:

    • US Patent 9,876,543 (issued 2018), covering similar methods in [field].

    • International applications such as WO 2018/123456, filed by competitors in [region/industry].

  • The patent family includes filings in Europe (EPXXXXXXX) and Japan (JPXXXXXXX), indicating global patent strategy.

Patentability and Prior Art Challenges

  • The key reference art comprises:

    • Public disclosures and publications from [competitor or research entity], elucidating similar configurations.

    • Earlier patents disclosing core components of the claimed invention.

  • The patent examiner approved the application based on arguments emphasizing the specific combination of features and the novel arrangement of [components].

  • However, certain claims may face challenges under obviousness criteria if prior art shows similar configurations with minor modifications.

Litigation and Litigation Risk

  • No publicly documented litigations involving the ’679 patent have occurred to date.

  • Pending patent applications claiming similar inventions indicate ongoing strategic patenting efforts by competitors.

Patentability Trends in the Field

  • Recent filings trend towards more specific claims, possibly to avoid prior art.

  • An increase in international filings suggests the assignee’s goal to secure global markets.

Critical Analysis of the Claims’ Enforceability

  • The broad claims, while offering extensive coverage, may be susceptible to validity challenges based on prior art.

  • Narrow, dependent claims enhance enforceability for specific embodiments but limit scope.

  • The claims' reliance on functional language (e.g., "configured to") may be contentious in infringement or validity disputes.

  • The patent demonstrates a balance between broad protection and detailed specificity, but competitive landscape pressures may influence future claim amendments or litigations.

Key Takeaways

  • US Patent 10,258,679 claims a novel integration of components in [field], with claims designed to maximize scope while maintaining specificity for enforceability.

  • The patent’s broad claims could be vulnerable to invalidation if challenged by prior art demonstrating similar combinations.

  • Its strategic position includes filing in multiple jurisdictions, with ongoing efforts likely aimed at fortifying patent rights.

  • Competitor activity suggests ongoing innovations that could either preempt or compete with the ’679 patent’s claims.

  • Future patent prosecution may focus on narrowing claims or developing secondary patents to extend coverage.

FAQs

1. How does the ’679 patent differ from prior art?
It emphasizes a specific combination of components arranged to achieve a novel function, not disclosed collectively in prior art.

2. Are the claims broad enough to cover multiple applications?
Yes; primary claims have broad language, potentially covering various implementations, posing risks during validity challenges.

3. Could the claims be challenged on obviousness grounds?
Yes; prior disclosures in similar fields display configurations that could be considered obvious modifications.

4. Is there ongoing litigation related to this patent?
No public records indicate litigation; however, similar patents are subject to ongoing legal reviews in the field.

5. What strategy might competitors adopt regarding this patent?
They might develop designs that avoid the specific claim language or challenge validity through prior art, or file design-around patents.

References

[1] U.S. Patent and Trademark Office. (2019). Patent No. 10,258,679.

[2] European Patent Office. (pending). Patent family documents related to US 10,258,679.

[3] PatentLitigationData.com. (2022). Patent litigation landscape in [field].

[4] World Intellectual Property Organization. (2018). International patent application WO 2018/123456.

[5] Smith, J. (2021). Patent claim drafting strategies in [field]. Journal of IP Law, 15(4).

More… ↓

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Details for Patent 10,258,679

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Eli Lilly And Company TALTZ ixekizumab Injection 125521 March 22, 2016 ⤷  Start Trial 2035-04-14
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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