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Last Updated: September 30, 2020

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Patent: 10,144,776

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Summary for Patent: 10,144,776
Title:Treatment of central nervous system disorders by intranasal administration of immunoglobulin G
Abstract: The present invention provides, among other aspects, methods and compositions for treating a central nervous system (CNS) disorder by delivering a therapeutically effective amount of a composition of pooled human immunoglobulin G (IgG) to the brain via intranasal administration of the composition directly to the olfactory epithelium of the nasal cavity. In particular, methods and compositions for treating Alzheimer\'s disease are provided.
Inventor(s): Frey; William H. (White Bear Lake, MN), Hanson; Leah Ranae Bresin (Vadnais Heights, MN), Pokropinski; Sharon (Schaumburg, IL), Rausa; Francisco M. (Vernon Hills, IL)
Assignee: Baxalta Incorporated (Bannockburn, IL) Baxalta GmbH (Zug, CH)
Application Number:15/335,027
Patent Claims:see list of patent claims

Details for Patent 10,144,776

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Csl Behring Ag CARIMUNE human immunoglobulin g INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 102367 1 2009-02-10   Start Trial Baxalta Incorporated (Bannockburn, IL) Baxalta GmbH (Zug, CH) 2033-02-26 search
Csl Behring Ag PRIVIGEN human immunoglobulin g LIQUID 125201 1 2009-01-20   Start Trial Baxalta Incorporated (Bannockburn, IL) Baxalta GmbH (Zug, CH) 2033-02-26 search
Bio Products Laboratory Limited GAMMAPLEX human immunoglobulin g SOLUTION 125329 1 2017-04-07   Start Trial Baxalta Incorporated (Bannockburn, IL) Baxalta GmbH (Zug, CH) 2033-02-26 search
Csl Behring Ag HIZENTRA human immunoglobulin g LIQUID 125350 1 2020-01-01   Start Trial Baxalta Incorporated (Bannockburn, IL) Baxalta GmbH (Zug, CH) 2033-02-26 search
Adma Biologics, Inc. ASCENIV human immunoglobulin g LIQUID 125590 1 2019-04-01   Start Trial Baxalta Incorporated (Bannockburn, IL) Baxalta GmbH (Zug, CH) 2033-02-26 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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