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Last Updated: August 4, 2021

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Patent: 10,023,608

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Summary for Patent: 10,023,608
Title:Protein purification methods to remove impurities
Abstract: Disclosed are methods of purifying a protein sample. More specifically, provide are methods of removing or reducing the amount of high molecular weight species and/or high mannose species from a protein sample using a mixed mode chromatography step and a hydrophobic interaction chromatography step.
Inventor(s): Ma; Junfen (Thousand Oaks, CA), Zhao; Xiaoyang (Moorpark, CA), Williamson; Brian (Camarillo, CA)
Assignee: AMGEN INC. (Thousand Oaks, CA)
Application Number:14/208,043
Patent Claims:see list of patent claims

Details for Patent 10,023,608

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Abbvie Inc HUMIRA adalimumab VIAL 125057 002 2002-12-31 ⤷  Free Forever Trial AMGEN INC. (Thousand Oaks, CA) 2033-03-13 RX search
Abbvie Inc HUMIRA adalimumab SYRINGE 125057 001 2002-12-31 ⤷  Free Forever Trial AMGEN INC. (Thousand Oaks, CA) 2033-03-13 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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