Patent: 10,023,608
✉ Email this page to a colleague
Summary for Patent: 10,023,608
Title: | Protein purification methods to remove impurities |
Abstract: | Disclosed are methods of purifying a protein sample. More specifically, provide are methods of removing or reducing the amount of high molecular weight species and/or high mannose species from a protein sample using a mixed mode chromatography step and a hydrophobic interaction chromatography step. |
Inventor(s): | Ma; Junfen (Thousand Oaks, CA), Zhao; Xiaoyang (Moorpark, CA), Williamson; Brian (Camarillo, CA) |
Assignee: | AMGEN INC. (Thousand Oaks, CA) |
Application Number: | 14/208,043 |
Patent Claims: | see list of patent claims |
Details for Patent 10,023,608
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | 12/31/2002 | ⤷ Try a Trial | 2033-03-13 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | 02/21/2008 | ⤷ Try a Trial | 2033-03-13 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | 04/24/2013 | ⤷ Try a Trial | 2033-03-13 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |