Last Updated: June 24, 2026

Patent: 10,016,434

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Summary for Patent: 10,016,434

Title:	Methods for the treatment of HER2 amplified cancer
Abstract:	Described herein are methods and compositions for treating HER2-amplified cancer. The methods include administering to an individual in need thereof ibrutinib.
Inventor(s):	Chen; Jun (San Jose, CA), Buggy; Joseph J. (Mountain View, CA), Elias; Laurence (Berkeley, CA)
Assignee:	Pharmacyclics LLC (Sunnyvale, CA)
Application Number:	15/652,470
Patent Claims:	see list of patent claims

Details for Patent 10,016,434

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genentech, Inc.	HERCEPTIN	trastuzumab	For Injection	103792	September 25, 1998	⤷ Start Trial	2037-07-18
Genentech, Inc.	HERCEPTIN	trastuzumab	For Injection	103792	February 10, 2017	⤷ Start Trial	2037-07-18
Genentech, Inc.	AVASTIN	bevacizumab	Injection	125085	February 26, 2004	⤷ Start Trial	2037-07-18
Genentech, Inc.	LUCENTIS	ranibizumab	Injection	125156	June 30, 2006	⤷ Start Trial	2037-07-18
Genentech, Inc.	LUCENTIS	ranibizumab	Injection	125156	August 10, 2012	⤷ Start Trial	2037-07-18
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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