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Generated: September 22, 2017

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Title:Processes of producing a fermentation product
Abstract: The invention relates to a process of process of producing a fermentation product, comprising: liquefying a starch-containing material to dextrins with an alpha-amylase in the presence of an asparaginase and/or an amino acid oxidase; saccharifying the dextrins to a sugar with a glucoamylase; and fermenting the sugar using a fermenting organism.
Inventor(s): Prata; Rogerio (Franklinton, NC), Robey; Alison (Sioux Falls, SD), Forman; Todd (Franklinton, NC), Clark; Suzanne (Franklinton, NC), Bordin; Eder Manzini (Curitiba, BR)
Assignee: NOVOZYMES NORTH AMERICA, INC. (Bagsvaerd, DK)
Application Number:14/707,786
Patent Claims:1. A process of producing a fermentation product, comprising (a) treating a plant extract containing amino acid(s) and soluble sugar(s) with an amino acid oxidase, an arginase, and/or an asparaginase; (b) producing molasses from the treated plant extract; (c) diluting the molasses; and (d) fermenting the diluted molasses with a fermenting organism to produce the fermentation product.

2. The process of claim 1, wherein the plant extract is treated with an asparaginase.

3. The process of claim 2, wherein the asparaginase is an enzyme of EC 3.5.1.1.

4. The process of claim 2, wherein the asparaginase is an enzyme of EC 3.5.1.38.

5. The process of claim 1, wherein the plant extract is treated with an arginase.

6. The process of claim 1, wherein the plant extract is treated with an amino acid oxidase.

7. The process of claim 6, wherein the amino acid oxidase is an enzyme of EC 1.4.3.2.

8. The process of claim 6, wherein the amino acid oxidase is an enzyme of EC 1.4.3.3.

9. The process of claim 1, wherein the plant extract is raw sugarcane juice or clarified sugarcane juice.

10. The process of claim 1, wherein the production of molasses comprises: clarification of the plant extract; concentration of sugars found in the clarified plant extract to form a syrup; and crystallization of sucrose from the syrup to form the molasses.

11. A process of producing a fermentation product, comprising (a) treating a plant extract containing amino acid(s) and soluble sugar(s) with an amino acid oxidase, an arginase, and/or an asparaginase; (b) producing molasses from the treated plant extract; (c) diluting the molasses; and (d) fermenting the diluted molasses with a fermenting organism to produce the fermentation product, wherein the plant extract is selected from the group consisting of sweet sorghum extract, sugar beet extract, sugar cane extract, sugar cane juice, clarified sugarcane juice, and combinations thereof.

12. The process of claim 11, wherein the plant extract is treated with an asparaginase.

13. The process of claim 11, wherein the asparaginase is an enzyme of EC 3.5.1.1.

14. The process of claim 11, wherein the asparaginase is an enzyme of EC 3.5.1.38.

15. The process of claim 11, wherein the plant extract is treated with an arginase.

16. The process of claim 11, wherein the plant extract is treated with an amino acid oxidase.

17. The process of claim 11, wherein the plant extract is treated with an arginase.

18. The process of claim 11, wherein the plant extract is treated with an amino acid oxidase.

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Inventors Patent Expiration Status Orphan Source
Merck
ELSPAR
asparaginase
VIAL1010630011978-01-10► Subscribe NOVOZYMES NORTH AMERICA, INC. (Bagsvaerd, DK) Prata; Rogerio (Franklinton, NC), Robey; Alison (Sioux Falls, SD), Forman; Todd (Franklinton, NC), Clark; Suzanne (Franklinton, NC), Bordin; Eder Manzini (Curitiba, BR) ► SubscribeRXsearch
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International Patent Family for Patent: ► Subscribe

Country Document Number Publication Date
Brazil112013012357Oct 11, 2016
Canada2817224May 24, 2012
China103797125Dec 07, 2016
China103797125May 14, 2014
European Patent Office2640840Sep 25, 2013
United States of America2013330785Dec 12, 2013
United States of America2015240265Aug 27, 2015
United States of America9057087Jun 16, 2015
World Intellectual Property Organization (WIPO)2012068047May 24, 2012
World Intellectual Property Organization (WIPO)2012068047Oct 17, 2013
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Serving 500+ biopharmaceutical companies globally:

Mallinckrodt
Teva
Dow
Daiichi Sankyo
Cantor Fitzgerald
Johnson and Johnson
UBS
US Army
Cerilliant
Medtronic

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