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Last Updated: April 26, 2024

Claims for Patent: 6,120,766


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Summary for Patent: 6,120,766
Title: CDW52-specific antibody for treatment of multiple sclerosis
Abstract:The invention relates to the use of an antibody recognizing the Cdw52 antigen in the treatment of multiple sclerosis. Preferably, the antibody is the humanized antibody in the humanized antibody CAMPATH-1H.
Inventor(s): Hale; Geoffrey (N/A), N/A (Cambridge, CB2 1QP, GB), Waldmann; Herman (Cambridge, CB2 1QP, GB)
Assignee:
Application Number:08/244,316
Patent Claims:1. A method for the treatment of a human subject suffering from multiple sclerosis which comprises administering to said subject an effective amount of a humanized antibody CAMPATH-1H and an effective amount of a steroid.

2. A method in accordance with claim 1, wherein the antibody is administered daily at a dose ranging from 1 to 100 mg per day for a period of 1 to 30 days.

3. A method in accordance with claim 2, wherein the antibody is administered daily at a dose ranging from 1 to 10 mg per day.

4. A method in accordance with claim 1, wherein the steroid is a hydrocortisone.

5. A method in accordance with claim 1, wherein the antibody was produced in Chinese Hamster Ovary (CHO) cells.

6. The method according to claim 4 wherein the hydrocortisone is methylprednisone.

Details for Patent 6,120,766

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genzyme Corporation CAMPATH alemtuzumab Injection 103948 05/07/2001 ⤷  Try a Trial 2017-09-19
Genzyme Corporation LEMTRADA alemtuzumab Injection 103948 11/14/2014 ⤷  Try a Trial 2017-09-19
Genzyme Corporation CAMPATH alemtuzumab Injection 103948 10/12/2004 ⤷  Try a Trial 2017-09-19
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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