Claims for Patent: 5,618,697
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Summary for Patent: 5,618,697
| Title: | Process for preparing a desired protein |
| Abstract: | A process for producing ripe human growth hormone is described which comprises introducing into bacteria a recombinant DNA vector comprising a DNA sequence encoding an amino-terminal extended human growth hormone which amino-terminal extension has a negatively charged amino acid sequence and has an even number of amino acids, growing the bacteria such that the amino-terminal extended human growth is expressed, separating the amino-terminal extended human grown hormone from contaminants, cleaving the amino-terminal extension with dipeptidyl aminopeptidase I to obtain ripe human growth hormone and isolating the ripe human growth hormone produced. |
| Inventor(s): | Henrik Dalb.o slashed.ge, John Pedersen, Thorkild Christensen, J.o slashed.rli W. Ringsted, Torben E. Jessen |
| Assignee: | Novo Nordisk Health Care AG |
| Application Number: | US08/372,692 |
| Patent Claims: |
Details for Patent 5,618,697
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Novo Nordisk Inc. | NORDITROPIN | somatropin | Injection | 021148 | June 20, 2000 | ⤷ Get Started Free | 2015-01-13 |
| Novo Nordisk Inc. | NORDITROPIN | somatropin | Injection | 021148 | October 01, 2004 | ⤷ Get Started Free | 2015-01-13 |
| Novo Nordisk Inc. | NORDITROPIN | somatropin | Injection | 021148 | March 10, 2009 | ⤷ Get Started Free | 2015-01-13 |
| Novo Nordisk Inc. | NORDITROPIN | somatropin | Injection | 021148 | March 01, 2010 | ⤷ Get Started Free | 2015-01-13 |
| Novo Nordisk Inc. | NORDITROPIN | somatropin | Injection | 021148 | January 23, 2015 | ⤷ Get Started Free | 2015-01-13 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
International Patent Family for US Patent 5,618,697
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 8604609 | ⤷ Get Started Free |
| World Intellectual Property Organization (WIPO) | 8402351 | ⤷ Get Started Free |
| United States of America | 5691169 | ⤷ Get Started Free |
| United States of America | 5679552 | ⤷ Get Started Free |
| United States of America | 5635604 | ⤷ Get Started Free |
| >Country | >Patent Number | >Estimated Expiration |
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