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Last Updated: December 29, 2025

Claims for Patent: 5,618,697


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Summary for Patent: 5,618,697
Title:Process for preparing a desired protein
Abstract:A process for producing ripe human growth hormone is described which comprises introducing into bacteria a recombinant DNA vector comprising a DNA sequence encoding an amino-terminal extended human growth hormone which amino-terminal extension has a negatively charged amino acid sequence and has an even number of amino acids, growing the bacteria such that the amino-terminal extended human growth is expressed, separating the amino-terminal extended human grown hormone from contaminants, cleaving the amino-terminal extension with dipeptidyl aminopeptidase I to obtain ripe human growth hormone and isolating the ripe human growth hormone produced.
Inventor(s):Henrik Dalb.o slashed.ge, John Pedersen, Thorkild Christensen, J.o slashed.rli W. Ringsted, Torben E. Jessen
Assignee:Novo Nordisk Health Care AG
Application Number:US08/372,692
Patent Claims:

Details for Patent 5,618,697

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Novo Nordisk Inc. NORDITROPIN somatropin Injection 021148 June 20, 2000 ⤷  Get Started Free 2015-01-13
Novo Nordisk Inc. NORDITROPIN somatropin Injection 021148 October 01, 2004 ⤷  Get Started Free 2015-01-13
Novo Nordisk Inc. NORDITROPIN somatropin Injection 021148 March 10, 2009 ⤷  Get Started Free 2015-01-13
Novo Nordisk Inc. NORDITROPIN somatropin Injection 021148 March 01, 2010 ⤷  Get Started Free 2015-01-13
Novo Nordisk Inc. NORDITROPIN somatropin Injection 021148 January 23, 2015 ⤷  Get Started Free 2015-01-13
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 5,618,697

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 8604609 ⤷  Get Started Free
World Intellectual Property Organization (WIPO) 8402351 ⤷  Get Started Free
United States of America 5691169 ⤷  Get Started Free
United States of America 5679552 ⤷  Get Started Free
United States of America 5635604 ⤷  Get Started Free
>Country >Patent Number >Estimated Expiration

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